Determine the necessary mass, volume, or concentration for preparing a solution.
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≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 16 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Sulfamethizole is a sulfathiazole antibacterial agent.
| ALogP | 0.5 |
|---|
| Pubchem Sid | 504750869 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504750869 |
| Sonrisas canónicas | CC1=NN=C(S1)NS(=O)(=O)C2=CC=C(C=C2)N |
| IUPAC Name | 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide |
| InChIKey | VACCAVUAMIDAGB-UHFFFAOYSA-N |
| INCHI | 1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13) |
| Isómeros SMILES | CC1=NN=C(S1)NS(=O)(=O)C2=CC=C(C=C2)N |
| WGK Alemania | 2 |
| RTECS | WP0875000 |
| PubChem CID | 5328 |
| Peso molecular | 270.33 |
| Beilstein | 255002 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Benzenesulfonamides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Aminobenzenesulfonamides |
| Alternative Parents | Benzenesulfonyl compounds Aniline and substituted anilines Organosulfonamides Thiadiazoles Heteroaromatic compounds Aminosulfonyl compounds Azacyclic compounds Primary amines Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Aminobenzenesulfonamide - Benzenesulfonyl group - Aniline or substituted anilines - Organosulfonic acid amide - Azole - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Thiadiazole - Aminosulfonyl compound - Heteroaromatic compound - Organoheterocyclic compound - Azacycle - Organonitrogen compound - Amine - Organic oxygen compound - Organic nitrogen compound - Organosulfur compound - Organopnictogen compound - Primary amine - Hydrocarbon derivative - Organic oxide - Aromatic heteromonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring. |
| External Descriptors | sulfonamide - thiadiazoles - sulfonamide antibiotic |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Jan 23, 2026 | S128341 | |
| Certificate of Analysis | Jan 23, 2026 | S128341 | |
| Certificate of Analysis | Jan 23, 2026 | S128341 | |
| Certificate of Analysis | Aug 19, 2025 | S128341 | |
| Certificate of Analysis | Aug 19, 2025 | S128341 | |
| Certificate of Analysis | Apr 01, 2024 | S128341 | |
| Certificate of Analysis | Apr 01, 2024 | S128341 | |
| Certificate of Analysis | Apr 01, 2024 | S128341 | |
| Certificate of Analysis | Mar 12, 2024 | S128341 | |
| Certificate of Analysis | Mar 12, 2024 | S128341 | |
| Certificate of Analysis | Mar 12, 2024 | S128341 | |
| Certificate of Analysis | Mar 29, 2023 | S128341 | |
| Certificate of Analysis | Mar 29, 2023 | S128341 | |
| Certificate of Analysis | Mar 29, 2023 | S128341 | |
| Certificate of Analysis | Mar 29, 2023 | S128341 |
| Sensibilidad | Light Sensitive |
|---|---|
| Punto de fusión (°C) | 210°C |
| Peso molecular | 270.300 g/mol |
| XLogP3 | 0.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 3 |
| Exact Mass | 270.025 Da |
| Monoisotopic Mass | 270.025 Da |
| Topological Polar Surface Area | 135.000 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 348.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Mingguo Peng, Yicui Wang, Chunge Wu, Xuewen Cai, Yao Wu, Erdeng Du, Lu Zheng, Jiajun Fu. (2023) Investigating sulfonamides - Human serum albumin interactions: A comprehensive approach using multi-spectroscopy, DFT calculations, and molecular docking. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, [PMID:37862782] [10.1016/j.bbrc.2023.10.040] |
| 2. Jing Wang, Yong Zhang, Fubin Liu, Ying Liu, Litao Wang, Guihua Gao. (2023) Preparation of a Multifunctional and Multipurpose Chitosan/Cyclodextrin/MIL-68(Al) Foam Column and Examining Its Adsorption Properties for Anionic and Cationic Dyes and Sulfonamides. ACS Omega, [PMID:37692232] [10.1021/acsomega.3c03897] |
| 3. Meiling Ping, Wenchao Lv, Chen Yang, Qian Chen, Zongwen Wang, Fengfu Fu. (2023) A Paper-Based Multicolor Colorimetric Aptasensor for the Visual Determination of Multiple Sulfonamides Based on Aptamer-Functionalized Magnetic Beads and NADH–Ascorbic Acid-Mediated Gold Nanobipyramids. Chemosensors, 11 (7): (386). [PMID:] [10.3390/chemosensors11070386] |
| 4. Zongwen Wang, Xiating Li, Feng Zhang, Yu Gao, Jintian Cheng, FengFu Fu. (2023) Regulating the Growth Rate of Gold Nanobipyramids via a HCl-NADH-Ascorbic Acid System toward a Dual-Channel Multicolor Colorimetric Immunoassay for Simultaneously Screening and Detecting Multiple Sulfonamides. ANALYTICAL CHEMISTRY, [PMID:37382204] [10.1021/acs.analchem.3c01928] |
| 5. Lin Li, Hongyu Zhang, Mengdan Zhang, Ting Wang, Xiaohong Hou. (2022) MIL-88B(Fe)/cellulose microspheres as sorbent for the fully automated dispersive pipette extraction towards trace sulfonamides in milk samples prior to UPLC-MS/MS analysis. ANALYTICA CHIMICA ACTA, [PMID:36257763] [10.1016/j.aca.2022.340420] |
| 6. Quan Chen, Peng Yi, Wei Dong, Yihui Chen, Liping He, Bo Pan. (2020) Decisive role of adsorption affinity in antibiotic adsorption on a positively charged MnFe2O4@CAC hybrid. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:32758730] [10.1016/j.scitotenv.2020.141019] |
| 7. Liu Yaqing, Lin Xiaodong, Ji Xiangyi, Hao Zhe, Tao Zhanhui. (2020) Smartphone-based enzyme-free fluorescence sensing of organophosphate DDVP. MICROCHIMICA ACTA, 187 (7): (1-8). [PMID:32613298] [10.1007/s00604-020-04384-7] |
| 8. Di Siyuan, Yu Jing, Chen Pin, Zhu Gangtian, Zhu Shukui. (2020) Net-like mesoporous carbon nanocomposites for magnetic solid-phase extraction of sulfonamides prior to their quantitation by UPLC-HRMS. MICROCHIMICA ACTA, 187 (2): (1-11). [PMID:31919594] [10.1007/s00604-019-4072-7] |
| 9. Minghuo Wu, Lin Fu, Yufeng Hu, Jingyun Su, Siyuan Jing, Hao Zhou, Jingjing Zhan. (2018) Multiplex On-Bead Isotope Dimethyl Labeling Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry for Quantitative Analysis of Sulfonamides in Estuarine Ice. ANALYTICAL CHEMISTRY, [PMID:30221932] [10.1021/acs.analchem.8b03220] |
| 10. Xiuna Jia, Pan Zhao, Xiu Ye, Lianjun Zhang, Ting Wang, Qinyu Chen, Xiaohong Hou. (2016) A novel metal-organic framework composite MIL-101(Cr)@GO as an efficient sorbent in dispersive micro-solid phase extraction coupling with UHPLC-MS/MS for the determination of sulfonamides in milk samples. TALANTA, [PMID:28411816] [10.1016/j.talanta.2016.08.086] |
| 11. Yazhen Li, Xuewen Wu, Zhaoqian Li, Shuxian Zhong, Weiping Wang, Aijun Wang, Jianrong Chen. (2015) Fabrication of CoFe2O4–graphene nanocomposite and its application in the magnetic solid phase extraction of sulfonamides from milk samples. TALANTA, [PMID:26452959] [10.1016/j.talanta.2015.08.006] |
| 12. Longcheng Xu, Jianming Pan, Jiangdong Dai, Xiuxiu Li, Hui Hang, Zhijing Cao, Yongsheng Yan. (2012) Preparation of thermal-responsive magnetic molecularly imprinted polymers for selective removal of antibiotics from aqueous solution. JOURNAL OF HAZARDOUS MATERIALS, [PMID:22795838] [10.1016/j.jhazmat.2012.06.056] |
| 13. Lina Gao, Junfei Wu, Hai-Bo Liu, Qian Zhao, Jing Wang. (2025) Metal-mediated chitosan@mesoporous silica-based ultrasensitive fluorescent probe for the ratiometic and colorimetric detection of tetracycline antibiotics. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39924023] [10.1016/j.ijbiomac.2025.140779] |
| 14. Sai Li, Shuangying Yu, Mengyao Zhang, Zeyi Li, Hui Yu, Zhongfu Xing, Beibei Mao, Pan Zhao. (2025) Monolithic and hierarchically porous biochar/cellulose aerogel as adsorbent for microextraction in packed syringe towards trace sulfonamides in water samples prior to UPLC-MS/MS. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:39893779] [10.1016/j.jpba.2025.116714] |
| 15. Qi Mengyu, Tu Chunyan, Li Zhaoqian, Wang Weiping, Chen Jianrong, Wang Ai-Jun. (2018) Determination of Sulfonamide Residues in Honey and Milk by HPLC Coupled with Novel Graphene Oxide/Polypyrrole Foam Material-Pipette Tip Solid Phase Extraction. Food Analytical Methods, 11 (10): (2885-2896). [PMID:] [10.1007/s12161-018-1271-5] |
| 16. Xiao-Ming Zou, Tiao Zhang, Yu-Hua Dong, Cui Hu, Li Yin, Yu-Ling Zheng, Mi Li, Xiao-Yu Xiao, Wei Hui. (2025) Enhanced removal of sulfonamide antibiotics in water using high-performance S-nZVI/BC derived from rice straw. JOURNAL OF ENVIRONMENTAL MANAGEMENT, [PMID:39756288] [10.1016/j.jenvman.2024.123955] |