Sulfopin - Moligand™, 10mM in DMSO , Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1, CAS No.2451481-08-4, Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1

CAS: 2451481-08-4 Cat. No.: S580530 Fórmula: C₁₁H₂₀ClNO₃S Peso molecular: 281.8 Número EC: 873-703-0 PubChem CID: 155804394

CALIDAD & PUREZA Moligand™, 10mM in DMSO

Synonyms

2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide | HY-139361 | Z3375875148 | 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxo-1lambda6-thiolan-3-yl)acetamide | EN300-6495949 | 2451481-08-4 | AKOS040759747 | PIN1-3 | GTPL11540 | sulfopin | SC

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Product description：

Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.

Especificaciones

Sinónimos

2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide | HY-139361 | Z3375875148 | 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxo-1lambda6-thiolan-3-yl)acetamide | EN300-6495949 | 2451481-08-4 | AKOS040759747 | PIN1-3 | GTPL11540 | sulfopin | SC

Especificaciones y pureza

Moligand™, 10mM in DMSO

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

INHIBITOR

Mecanismo de acción

Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1

Nombres e identificadores

Sonrisas canónicas

CC(C)(C)CN(C1CCS(=O)(=O)C1)C(=O)CCl

IUPAC Name

2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide

InChIKey

NMHVAHHYKGXBMY-UHFFFAOYSA-N

INCHI

1S/C11H20ClNO3S/c1-11(2,3)8-13(10(14)6-12)9-4-5-17(15,16)7-9/h9H,4-8H2,1-3H3

Isómeros SMILES

CC(C)(C)CN(C1CCS(=O)(=O)C1)C(=O)CCl

CAS alternativo

2451481-08-4

PubChem CID

155804394

Peso molecular

281.8

Objetivos asociados (humanos)

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (0 Activities)

Discover Target: PIN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Peso molecular: 281.800 g/mol
• XLogP3: 1.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 281.085 Da
• Monoisotopic Mass: 281.085 Da
• Topological Polar Surface Area: 62.800 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 381.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1