SW2_152F - ≥99% , CAS No.S659228

CAS: S659228 Cat. No.: S659228 Fórmula: C₄₅H₆₂Cl₃N₇O₈ Peso molecular: 935.37

GRADE & PURITY ≥99%

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

SW2_152F is a potent, selective chromobox 2 chromodomain (CBX2 ChD) inhibitor with a K d of 80 nM. SW2_152F displays 24-1000-fold selectivity for CBX2 ChD over other CBX paralogs in vitro.

Appearance:Solid

IC50& Target:Kd: 80 nM (chromobox 2 chromodomain)

In Vitro:SW2_152F inhibits CBX2 chromatin binding in cells, and blocks neuroendocrine differentiation of prostate cancer cell lines in response to androgen deprivation. MCE has not independently confirmed the accuracy of these methods. They are for reference

Biological Activity:SW2_152F is a potent, selective chromobox 2 chromodomain (CBX2 ChD) inhibitor with a K d of 80 nM. SW2_152F displays 24-1000-fold selectivity for CBX2 ChD over other CBX paralogs in vitro.

Specifications

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -20°C,Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99%

Nombres e identificadores

• Sonrisas canónicas: ClC1=CC(Cl)=CC(C(N[C@@H](CC2=CC(Cl)=C(O)C=C2)C(N[C@@H](C3CCCC3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN(CC)CC)C(N[C@@H](CO)C(NCC#C)=O)=O)=O)=O)=O)=O)=C1
• Peso molecular: 935.37

Propiedades químicas y físicas

• Solubilidad: DMSO : 175 mg/mL (187.09 mM; Need ultrasonic)

Preguntas frecuentes

What are the CAS number, molecular formula and molecular weight?

The CAS Number is S659228, the molecular formula is C45H62Cl3N7O8, and the molecular weight is 935.37 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.