SW2_152F - ≥99% , CAS No.S659228

CAS: S659228 Cat. No.: S659228 Peso molecular: 935.37

GRADE & PURITY ≥99%

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

SW2_152F is a potent, selective chromobox 2 chromodomain (CBX2 ChD) inhibitor with a K d of 80 nM. SW2_152F displays 24-1000-fold selectivity for CBX2 ChD over other CBX paralogs in vitro.

Appearance:Solid

IC50& Target:Kd: 80 nM (chromobox 2 chromodomain)

In Vitro:SW2_152F inhibits CBX2 chromatin binding in cells, and blocks neuroendocrine differentiation of prostate cancer cell lines in response to androgen deprivation. MCE has not independently confirmed the accuracy of these methods. They are for reference

Biological Activity:SW2_152F is a potent, selective chromobox 2 chromodomain (CBX2 ChD) inhibitor with a K d of 80 nM. SW2_152F displays 24-1000-fold selectivity for CBX2 ChD over other CBX paralogs in vitro.

Specifications

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

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Pureza

≥99%

Nombres e identificadores

• Sonrisas canónicas: ClC1=CC(Cl)=CC(C(N[C@@H](CC2=CC(Cl)=C(O)C=C2)C(N[C@@H](C3CCCC3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN(CC)CC)C(N[C@@H](CO)C(NCC#C)=O)=O)=O)=O)=O)=O)=C1
• Peso molecular: 935.37

Propiedades químicas y físicas

• Solubilidad: DMSO : 175 mg/mL (187.09 mM; Need ultrasonic)