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EIF2AK3

DescripciónEukaryotic translation initiation factor 2-alpha kinase 3

Gene and Protein Information

Gene ID9451
Uniprot Accession IDs Q9NZJ5 A0AVH1 A0AVH2 B2RCU9 O95846 Q53QY0 Q53SB1
Ensembl ID ENSP00000307235
Symbol PEK PERK PEK WRS PERK
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
Sequence
MERAISPGLLVRALLLLLLLLGLAARTVAAGRARGLPAPTAEAAFGLGAAAAPTSATRVPAAGAVAAAEVTVEDAEALPAAAGEQEPRGPEPDDETELRPRGRSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGALFQWDQDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDSDEMEQEEDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTSYTSNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPSSPKALESVTNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWNDIKNSGYISRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFATKEHIEIIAPSPQRSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNGRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp459388EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 39598VGNC:237OMA, EggNOG
Macaque699575EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 39544Inparanoid, OMA, EggNOG
Mouse13666Eif2ak3eukaryotic translation initiation factor 2 alpha kinase 310090MGI:1341830Inparanoid, OMA, EggNOG
Rat29702Eif2ak3eukaryotic translation initiation factor 2 alpha kinase 310116RGD:70884Inparanoid, OMA, EggNOG
Dog475756EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 39615VGNC:40258Inparanoid, OMA, EggNOG
Horse100066488EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 39796VGNC:17479Inparanoid, OMA, EggNOG
Cow535820EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 39913VGNC:28382Inparanoid, OMA, EggNOG
Pig100513348EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 39823Inparanoid, OMA, EggNOG
Opossum100029557EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 313616Inparanoid, EggNOG
Platypus100081193EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 39258Inparanoid, OMA, EggNOG
Chicken422930EIF2AK3eukaryotic translation initiation factor 2 alpha kinase 39031CGNC:11912Inparanoid, OMA, EggNOG
Anole lizard100551680eif2ak3eukaryotic translation initiation factor 2 alpha kinase 328377Inparanoid, OMA, EggNOG
Xenopus100190763eif2ak3eukaryotic translation initiation factor 2 alpha kinase 38364XB-GENE-989849Inparanoid, OMA, EggNOG
Zebrafish559564eif2ak3eukaryotic translation initiation factor 2-alpha kinase 37955ZDB-GENE-050414-2Inparanoid, OMA, EggNOG
C. elegans181334pek-1Eukaryotic translation initiation factor 2-alpha kinase pek-16239Inparanoid, OMA, EggNOG
Fruitfly40653PEKpancreatic eIF-2alpha kinase7227FBgn0037327Inparanoid, EggNOG

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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