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EIF2AK4

DescripcióneIF-2-alpha kinase GCN2

Gene and Protein Information

Gene ID440275
Uniprot Accession IDs Q9P2K8 C9JEC4 Q69YL7 Q6DC97 Q96GN6 Q9H5K1 Q9NSQ3 Q9NSZ5 Q9UJ56
Ensembl ID ENSP00000263791
Symbol GCN2 KIAA1338 GCN2 PVOD2
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
Sequence
MAGGRGAPGRGRDEPPESYPQRQDHELQALEAIYGADFQDLRPDACGPVKEPPEINLVLYPQGLTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGEVMIFELAYHVQSFLSEHNKPPPKSFHEEMLERRAQEEQQRLLEAKRKEEQEQREILHEIQRRKEEIKEEKKRKEMAKQERLEIASLSNQDHTSKKDPGGHRTAAILHGGSPDFVGNGKHRANSSGRSRRERQYSVCNSEDSPGSCEILYFNMGSPDQLMVHKGKCIGSDEQLGKLVYNALETATGGFVLLYEWVLQWQKKMGPFLTSQEKEKIDKCKKQIQGTETEFNSLVKLSHPNVVRYLAMNLKEQDDSIVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNSVVHKVLSASNVLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRFSDNALPYKTGKKGDVWRLGLLLLSLSQGQECGEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFINPQPKMPLVEQSPEDSEGQDYVETVIPSNRLPSAAFFSETQRQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASRQFRRIKGEVTLLSRLHHENIVRYYNAWIERHERPAGPGTPPPDSGPLAKDDRAARGQPASDTDGLDSVEAAAPPPILSSSVEWSTSGERSASARFPATGPGSSDDEDDDEDEHGGVFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEKNGCHESEPSVTTEAVHYLYIQMEYCEKSTLRDTIDQGLYRDTVRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFSADSKQDDQTGDLIKSDPSGHLTGMVGTALYVSPEVQGSTKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSPKFPEDFDDGEHAKQKSVISWLLNHDPAKRPTATELLKSELLPPPQMEESELHEVLHHTLTNVDGKAYRTMMAQIFSQRISPAIDYTYDSDILKGNFSIRTAKMQQHVCETIIRIFKRHGAVQLCTPLLLPRNRQIYEHNEAALFMDHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIERVFRPRKLDRFHPKELLECAFDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKLSQVYIILYDAVTEKLTRREVEAKFCNLSLSSNSLCRLYKFIEQKGDLQDLMPTINSLIKQKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYKVQQHNGIIFQFVAFIKRRQRAVPEILAAGGRYDLLIPQFRGPQALGPVPTAIGVSIAIDKISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKLRTKVTDERNGREASDNLAVQNLKGSFSNASGLFEIHGATVVPIVSVLAPEKLSASTRRRYETQVQTRLQTSLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp453321EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 49598VGNC:2490OMA, EggNOG
Mouse27103Eif2ak4eukaryotic translation initiation factor 2 alpha kinase 410090MGI:1353427Inparanoid, OMA, EggNOG
Rat114859Eif2ak4eukaryotic translation initiation factor 2 alpha kinase 410116RGD:1311439Inparanoid, OMA, EggNOG
Dog478257EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 49615VGNC:40259Inparanoid, OMA, EggNOG
Horse100071494EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 49796VGNC:17480Inparanoid, OMA, EggNOG
Cow513829EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 49913VGNC:28383Inparanoid, OMA, EggNOG
Opossum100031798EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 413616Inparanoid, EggNOG
PlatypusEIF2AK4eukaryotic translation initiation factor 2 alpha kinase 4 [Source:HGNC Symbol;Acc:HGNC:19687]9258OMA, EggNOG
Chicken423285EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 49031CGNC:7318Inparanoid, OMA
Anole lizard100552145eif2ak4eukaryotic translation initiation factor 2 alpha kinase 428377Inparanoid, OMA, EggNOG
Xenopuseif2ak4eukaryotic translation initiation factor 2 alpha kinase 4 [Source:Xenbase;Acc:XB-GENE-967321]8364OMA, EggNOG
C. elegans174953gcn-2Eukaryotic translation initiation factor 2-alpha kinase gcn-26239Inparanoid, OMA
Fruitfly43709Gcn2CG1609 gene product from transcript CG1609-RA7227FBgn0019990Inparanoid, EggNOG
S.cerevisiae851877GCN2serine/threonine-protein kinase GCN24932S000002691Inparanoid, OMA, EggNOG

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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