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MAP3K10

DescripciónMitogen-activated protein kinase kinase kinase 10

Gene and Protein Information

Gene ID4294
Uniprot Accession IDs Q02779 Q12761 Q14871
Ensembl ID ENSP00000253055
Symbol MLK2 MST MST MLK2 MEKK10
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MEEEEGAVAKEWGTTPAGPVWTAVFDYEAAGDEELTLRRGDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMCQLSQEKPRVRKRKGNFKRSRLLKLREGGSHISLPSGFEHKITVQASPTLDKRKGSDGASPPASPSIIPRLRAIRLTPVDCGGSSSGSSSGGSGTWSRGGPPKKEELVGGKKKGRTWGPSSTLQKERVGGEERLKGLGEGSKQWSSSAPNLGKSPKHTPIAPGFASLNEMEEFAEAEDGGSSVPPSPYSTPSYLSVPLPAEPSPGARAPWEPTPSAPPARWGHGARRRCDLALLGCATLLGAVGLGADVAEARAADGEEQRRWLDGLFFPRAGRFPRGLSPPARPHGRREDVGPGLGLAPSATLVSLSSVSDCNSTRSLLRSDSDEAAPAAPSPPPSPPAPTPTPSPSTNPLVDLELESFKKDPRQSLTPTHVTAACAVSRGHRRTPSDGALGQRGPPEPAGHGPGPRDLLDFPRLPDPQALFPARRRPPEFPGRPTTLTFAPRPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQPTLLDMDMEGQNQDSTVPLCGAHGSH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp468880MAP3K10mitogen-activated protein kinase kinase kinase 109598VGNC:11235OMA, EggNOG
Macaque700477MAP3K10mitogen-activated protein kinase kinase kinase 109544Inparanoid, OMA, EggNOG
Mouse269881Map3k10mitogen-activated protein kinase kinase kinase 1010090MGI:1346879Inparanoid, OMA, EggNOG
Rat308463Map3k10mitogen activated protein kinase kinase kinase 1010116RGD:1308381Inparanoid, OMA, EggNOG
Dog484504MAP3K10mitogen-activated protein kinase kinase kinase 109615VGNC:53748Inparanoid, OMA, EggNOG
CowMAP3K10mitogen-activated protein kinase kinase kinase 10 [Source:HGNC Symbol;Acc:HGNC:6849]9913OMA, EggNOG
Pig100521453MAP3K10mitogen-activated protein kinase kinase kinase 109823OMA, EggNOG
Opossum100017495MAP3K10mitogen-activated protein kinase kinase kinase 1013616Inparanoid, OMA, EggNOG
Anole lizard100565973map3k10mitogen-activated protein kinase kinase kinase 1028377Inparanoid, OMA
Xenopus100488058map3k10mitogen-activated protein kinase kinase kinase 108364XB-GENE-920944Inparanoid, OMA
Zebrafish560932map3k10mitogen-activated protein kinase kinase kinase 107955ZDB-GENE-050419-112Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    MLK family    /    MLK subfamily    /    Mitogen-activated protein kinase kinase kinase 10

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

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