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MAP3K12

DescripciónMitogen-activated protein kinase kinase kinase 12

Gene and Protein Information

Gene ID7786
Uniprot Accession IDs Q12852 B3KSS9 G3V1Y2 Q86VQ5 Q8WY25
Ensembl ID ENSP00000448689
Symbol ZPK DLK MUK ZPK ZPKP1 MEKK12
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTHVLQLHEQDAGGPGGAAGSPESRASRVRADEVRLQCQSGSGFLEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVPQKLSPHSKRPDILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLPGLRTAVPPHEPGGPGSPGGLGGGPSAWEACPPALRGLHHDLLLRKMSSSSPDLLSAALGSRGRGATGGAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTSGRGGSRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELTSSQRWPQSLNMRQSLSTFSSENPSDGEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDPPPSEVIPGPEPSSLPIPHQELLRERGPPNSEDSDCDSTELDNSNSVDALRPPASLPP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp451940MAP3K12mitogen-activated protein kinase kinase kinase 129598VGNC:13213OMA, EggNOG
Macaque703059MAP3K12mitogen-activated protein kinase kinase kinase 129544Inparanoid, OMA, EggNOG
Mouse26404Map3k12mitogen-activated protein kinase kinase kinase 1210090MGI:1346881Inparanoid, OMA, EggNOG
Rat25579Map3k12mitogen activated protein kinase kinase kinase 1210116RGD:3988Inparanoid, OMA, EggNOG
Dog607170MAP3K12mitogen-activated protein kinase kinase kinase 129615VGNC:42968Inparanoid, OMA
Horse100064002MAP3K12mitogen-activated protein kinase kinase kinase 129796VGNC:19931Inparanoid, OMA
Cow505427MAP3K12mitogen-activated protein kinase kinase kinase 129913VGNC:31190Inparanoid, OMA
Pig100517714MAP3K12mitogen-activated protein kinase kinase kinase 129823Inparanoid, OMA
Anole lizard100553164map3k12mitogen-activated protein kinase kinase kinase 1228377Inparanoid, OMA
Xenopus100488307map3k12mitogen-activated protein kinase kinase kinase 128364XB-GENE-482768Inparanoid, OMA
Zebrafish404626map3k12mitogen-activated protein kinase kinase kinase 127955ZDB-GENE-040426-2436Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    MLK family    /    Mitogen-activated protein kinase kinase kinase 12

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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