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MAP3K8

DescripciónMitogen-activated protein kinase kinase kinase 8

Gene and Protein Information

Gene ID1326
Uniprot Accession IDs P41279 A8K2Q5 D3DRX1 Q14275 Q5T855 Q9HC81
Ensembl ID ENSP00000263056
Symbol COT ESTF COT EST ESTF TPL2 AURA2 MEKK8 Tpl-2 c-COT
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MEYMSTGSDNKEEIDLLIKHLNVSDVIDIMENLYASEEPAVYEPSLMTMCQDSNQNDERSKSLLLSGQEVPWLSSVRYGTVEDLLAFANHISNTAKHFYGQRPQESGILLNMVITPQNGRYQIDSDVLLIPWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALLERKRLLSRKELELPENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEYG
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp450384MAP3K8mitogen-activated protein kinase kinase kinase 89598VGNC:7238OMA, EggNOG
Macaque696936MAP3K8mitogen-activated protein kinase kinase kinase 89544OMA, EggNOG
Mouse26410Map3k8mitogen-activated protein kinase kinase kinase 810090MGI:1346878Inparanoid, OMA, EggNOG
Rat116596Map3k8mitogen-activated protein kinase kinase kinase 810116RGD:620969Inparanoid, OMA, EggNOG
Dog487085MAP3K8mitogen-activated protein kinase kinase kinase 89615VGNC:42979Inparanoid, OMA, EggNOG
Horse100063602MAP3K8mitogen-activated protein kinase kinase kinase 89796VGNC:19943Inparanoid, OMA, EggNOG
Cow535622MAP3K8mitogen-activated protein kinase kinase kinase 89913VGNC:31202Inparanoid, OMA, EggNOG
Pig100622217MAP3K8mitogen-activated protein kinase kinase kinase 89823OMA, EggNOG
Opossum100018684MAP3K8mitogen-activated protein kinase kinase kinase 813616Inparanoid, OMA, EggNOG
Platypus100076215MAP3K8mitogen-activated protein kinase kinase kinase 89258Inparanoid, OMA, EggNOG
Chicken420479MAP3K8mitogen-activated protein kinase kinase kinase 89031CGNC:5558Inparanoid, OMA, EggNOG
Anole lizard100562883map3k8mitogen-activated protein kinase kinase kinase 828377Inparanoid, OMA, EggNOG
Xenopus100493069map3k8mitogen-activated protein kinase kinase kinase 88364XB-GENE-958505Inparanoid, OMA, EggNOG
Zebrafish563727map3k8mitogen-activated protein kinase kinase kinase 87955ZDB-GENE-100316-8OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    STE group    /    STE-UNIQUE family    /    Mitogen-activated protein kinase kinase kinase 8

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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