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MAP3K3

DescripciónMitogen-activated protein kinase kinase kinase 3

Gene and Protein Information

Gene ID4215
Uniprot Accession IDs Q99759 B2RCW2 D3DU15 Q5BKZ6 Q8N3I9
Ensembl ID ENSP00000354927
Symbol MAPKKK3 MEKK3 MEKK3 MAPKKK3
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MDEQEALNSIMNDLVALQMNRRHRMPGYETMKNKDTGHSNRQSDVRIKFEHNGERRIIAFSRPVKYEDVEHKVTTVFGQPLDLHYMNNELSILLKNQDDLDKAIDILDRSSSMKSLRILLLSQDRNHNSSSPHSGVSRQVRIKASQSAGDINTIYQPPEPRSRHLSVSSQNPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETSEQCMLDPLSSAENSLSGSCQSLDRSADSPSFRKSRMSRAQSFPDNRQEYSDRETQLYDKGVKGGTYPRRYHVSVHHKDYSDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYLDPRGRLRSADSENALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLMY
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp468286MAP3K3mitogen-activated protein kinase kinase kinase 39598VGNC:9367OMA, EggNOG
Macaque717866MAP3K3mitogen-activated protein kinase kinase kinase 39544Inparanoid, OMA, EggNOG
Mouse26406Map3k3mitogen-activated protein kinase kinase kinase 310090MGI:1346874Inparanoid, OMA, EggNOG
Rat303604Map3k3mitogen activated protein kinase kinase kinase 310116RGD:1304575Inparanoid, OMA
Dog480481MAP3K3mitogen-activated protein kinase kinase kinase 39615VGNC:42973Inparanoid, OMA, EggNOG
Horse100064751MAP3K3mitogen-activated protein kinase kinase kinase 39796VGNC:19937Inparanoid, OMA, EggNOG
Cow508943MAP3K3mitogen-activated protein kinase kinase kinase 39913VGNC:31196Inparanoid, OMA, EggNOG
Pig100513491MAP3K3mitogen-activated protein kinase kinase kinase 39823Inparanoid, OMA, EggNOG
Opossum100025970MAP3K3mitogen-activated protein kinase kinase kinase 313616Inparanoid, OMA, EggNOG
Chicken419954MAP3K3mitogen-activated protein kinase kinase kinase 39031CGNC:323Inparanoid, OMA
Anole lizard100557698map3k3mitogen-activated protein kinase kinase kinase 328377Inparanoid, OMA, EggNOG
XenopusXB-GENE-986927Putative ortholog of mitogen-activated protein kinase kinase kinase 3 (EC 2.7.1.37) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3), 1 of 1 [Source:Xenbase;Acc:XB-GENE-986927]8364OMA, EggNOG
Zebrafish560211map3k3mitogen-activated protein kinase kinase kinase 37955ZDB-GENE-070910-1Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    STE group    /    STE11 family    /    Mitogen-activated protein kinase kinase kinase 3

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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