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BMPR2

DescripciónBone morphogenetic protein receptor type-2

Gene and Protein Information

Gene ID659
Uniprot Accession IDs Q13873 Q13161 Q16569 Q4ZG08 Q53SA5 Q585T8 BMP type-2 receptor
Ensembl ID ENSP00000363708
Symbol PPH1 BMR2 PPH1 BMPR3 BRK-3 POVD1 T-ALK BMPR-II
FamilyBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MTSSLQRPWRVPWLPWTILLVSTAAASQNQERLCAFKDPYQQDLGIGESRISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLSPPHSFNRDETIIIALASVSVLAVLIVALCFGYRMLTGDRKQGLHSMNMMEAAASEPSLDLDNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSIVKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTTGLTPSTGMTTISEMPYPDETNLHTTNVAQSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSLKQFSGPDPLSSTSSSLLYPLIKLAVEATGQQDFTQTANGQACLIPDVLPTQIYPLPKQQNLPKRPTSLPLNTKNSTKEPRLKFGSKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRNHSVNSHAATTQYANGTVLSGQTTNIVTHRAQEMLQNQFIGEDTRLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLEGGRTNSNNNNSNPCSEQDVLAQGVPSTAADPGPSKPRRAQRPNSLDLSATNVLDGSSIQIGESTQDGKSGSGEKIKKRVKTPYSLKRWRPSTWVISTESLDCEVNNNGSNRAVHSKSSTAVYLAEGGTATTMVSKDIGMNCL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp459885BMPR2bone morphogenetic protein receptor type 29598VGNC:105OMA, EggNOG
Macaque704088BMPR2bone morphogenetic protein receptor type 29544Inparanoid, OMA, EggNOG
Mouse12168Bmpr2bone morphogenetic protein receptor, type II (serine/threonine kinase)10090MGI:1095407Inparanoid, OMA, EggNOG
Rat140590Bmpr2bone morphogenetic protein receptor type 210116RGD:71082Inparanoid, OMA, EggNOG
Dog478875BMPR2bone morphogenetic protein receptor type 29615VGNC:38486Inparanoid, OMA, EggNOG
Horse100067195BMPR2bone morphogenetic protein receptor type 29796VGNC:15853Inparanoid, OMA, EggNOG
Cow407127BMPR2bone morphogenetic protein receptor type 29913VGNC:26526Inparanoid, OMA, EggNOG
Pig100127483BMPR2bone morphogenetic protein receptor type 29823Inparanoid, OMA
Opossum100018765BMPR2bone morphogenetic protein receptor type 213616Inparanoid, OMA, EggNOG
PlatypusBMPR2bone morphogenetic protein receptor type 2 [Source:HGNC Symbol;Acc:HGNC:1078]9258OMA, EggNOG
Chicken374147BMPR2bone morphogenetic protein receptor type 29031CGNC:6414OMA, EggNOG
Anole lizard100553521bmpr2bone morphogenetic protein receptor type 228377Inparanoid, OMA, EggNOG
Xenopus100494339bmpr2bone morphogenetic protein receptor type II8364XB-GENE-479990Inparanoid, OMA, EggNOG
Zebrafish555655bmpr2bbone morphogenetic protein receptor, type II b (serine/threonine kinase)7955ZDB-GENE-070618-2Inparanoid, OMA, EggNOG
Fruitfly44096witwishful thinking7227FBgn0024179Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Bone morphogenetic protein receptor type-2
protein    /    receptor    /    TGF-beta receptor    /    Bone morphogenetic protein receptor type-2
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Bone morphogenetic protein receptor type-2
protein    /    receptor    /    protein kinase    /    Bone morphogenetic protein receptor type-2
protein    /    receptor    /    transferase    /    Bone morphogenetic protein receptor type-2
protein    /    receptor    /    kinase    /    Bone morphogenetic protein receptor type-2
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 2 subfamily    /    Bone morphogenetic protein receptor type-2

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

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