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| Descripción | Alpha-2-macroglobulin |
|---|
Gene and Protein Information
| Gene ID | 2 |
|---|---|
| Uniprot Accession IDs | P01023 Q13677 Q59F47 Q5QTS0 Q68DN2 Q6PIY3 Q6PN97 Alpha-2-M |
| Ensembl ID | ENSP00000323929 |
| Symbol | CPAMD5 A2MD CPAMD5 FWP007 S863-7 |
| Family | Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. |
| Sequence | MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Nombre | NIF | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Macaque | 716834 | A2M | alpha-2-macroglobulin | 9544 | Inparanoid, OMA | |
| Mouse | 232345 | A2m | alpha-2-macroglobulin | 10090 | MGI:2449119 | Inparanoid, OMA, EggNOG |
| Rat | 100911545 | LOC100911545 | alpha-2-macroglobulin-like | 10116 | RGD:6492449 | Inparanoid, OMA |
| Cow | 513856 | A2M | alpha-2-macroglobulin | 9913 | Inparanoid, OMA | |
| Pig | 403166 | A2M | alpha-2-macroglobulin | 9823 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / enzyme modulator / complement component / Alpha-2-macroglobulin
protein / enzyme modulator / cytokine / Alpha-2-macroglobulin
protein / enzyme modulator / serine protease inhibitor / Alpha-2-macroglobulin
protein / enzyme modulator / complement component / Alpha-2-macroglobulin
protein / enzyme modulator / cytokine / Alpha-2-macroglobulin
protein / enzyme modulator / serine protease inhibitor / Alpha-2-macroglobulin
DTO Classes
protein / Enzyme modulator / Protease inhibitor / Serine protease inhibitor / Alpha-2-macroglobulin
protein / Enzyme modulator / Protease inhibitor / Serine protease inhibitor / Alpha-2-macroglobulin
Associated Recombinant Proteins
| Nombre | Specification and purity | Expression system | Protein label | Disponibilidad | Mostrar detalles |
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Associated Antibodies
| Nombre | Specifications | Species reactivity | Aplicación | Disponibilidad | Mostrar detalles |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Nombre | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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