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ABCC1

DescripciónMultidrug resistance-associated protein 1

Gene and Protein Information

Gene ID4363
Uniprot Accession IDs P33527 A3RJX2 C9JPJ4 O14819 O43333 P78419 Q59GI9 Q9UQ97 Q9UQ99 Q9UQA0
Ensembl ID ENSP00000382342
Symbol MRP MRP1 MRP ABCC GS-X MRP1 ABC29
FamilyBelongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Sequence
MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp453952ABCC1ATP binding cassette subfamily C member 19598VGNC:51175OMA, EggNOG
Macaque717857ABCC1ATP binding cassette subfamily C member 19544OMA, EggNOG
Mouse17250Abcc1ATP-binding cassette, sub-family C (CFTR/MRP), member 110090MGI:102676Inparanoid, OMA, EggNOG
Rat24565Abcc1ATP binding cassette subfamily C member 110116RGD:3112Inparanoid, OMA
Dog403453ABCC1ATP binding cassette subfamily C member 19615VGNC:54275Inparanoid, OMA, EggNOG
Horse791240ABCC1ATP binding cassette subfamily C member 19796VGNC:14913Inparanoid, OMA
Cow281588ABCC1ATP binding cassette subfamily C member 19913VGNC:25468Inparanoid, OMA
Opossum100023220ABCC1ATP binding cassette subfamily C member 113616Inparanoid, OMA, EggNOG
PlatypusABCC1ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51]9258OMA, EggNOG
Chicken395416ABCC1ATP binding cassette subfamily C member 19031CGNC:49308Inparanoid, OMA, EggNOG
Xenopusabcc1ATP binding cassette subfamily C member 1 [Source:Xenbase;Acc:XB-GENE-960171]8364OMA, EggNOG
S.cerevisiae851713YCF1ATP-binding cassette glutathione S-conjugate transporter YCF14932S000002542OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    ATP-binding cassette (ABC) transporter    /    Multidrug resistance-associated protein 1
DTO Classes
protein    /    Transporter    /    ATP-binding cassette transporter family    /    ABCC subfamily    /    Multidrug resistance-associated protein 1

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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