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DNMT1

DescriptionDNA (cytosine-5)-methyltransferase 1

Gene and Protein Information

Gene ID1786
Uniprot Accession IDs P26358 A0AV63 B7ZLW6 Q9UHG5 Q9ULA2 Q9UMZ6 Dnmt1
Ensembl ID ENSP00000352516
Symbol AIM CXXC9 DNMT AIM DNMT MCMT CXXC9 HSN1E ADCADN m.HsaI
FamilyBelongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Sequence
MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQACEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESASAKIKEEEAAKD
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp107969662DNMT1DNA methyltransferase 19598VGNC:10201OMA, EggNOG
Macaque574321DNMT1DNA methyltransferase 19544Inparanoid, OMA, EggNOG
Mouse13433Dnmt1DNA methyltransferase (cytosine-5) 110090MGI:94912Inparanoid, OMA, EggNOG
Rat84350Dnmt1DNA methyltransferase 110116RGD:620979Inparanoid, OMA, EggNOG
Dog476715DNMT1DNA methyltransferase 19615Inparanoid, EggNOG
Horse100058341DNMT1DNA methyltransferase 19796VGNC:17255Inparanoid, OMA, EggNOG
Cow281119DNMT1DNA methyltransferase 19913VGNC:28145Inparanoid, OMA, EggNOG
Pig606746DNMT1DNA methyltransferase 19823Inparanoid, OMA, EggNOG
Opossum100013445LOC100013445DNA (cytosine-5)-methyltransferase 1-like13616OMA, EggNOG
Anole lizard100565926dnmt1DNA methyltransferase 128377Inparanoid, OMA, EggNOG
Xenopus100151716dnmt1DNA methyltransferase 18364XB-GENE-965562Inparanoid, OMA, EggNOG
Zebrafish30430dnmt1DNA (cytosine-5-)-methyltransferase 17955ZDB-GENE-990714-15Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Epigenetic regulator    /    Writer    /    DNA methyltransferase    /    DNA (cytosine-5)-methyltransferase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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