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ERCC2

DescripciónGeneral transcription and DNA repair factor IIH helicase subunit XPD

Gene and Protein Information

Gene ID2068
Uniprot Accession IDs P18074 Q2TB78 Q2YDY2 Q7KZU6 Q8N721 TFIIH subunit XPD
Ensembl ID ENSP00000375809
Symbol XPD XPDC EM9 TTD XPD TTD1 COFS2 TFIIH
FamilyBelongs to the helicase family. RAD3/XPD subfamily.
Sequence
MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp456124ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit9598VGNC:7479OMA, EggNOG
Macaque715485ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit9544Inparanoid, OMA, EggNOG
Mouse13871Ercc2excision repair cross-complementing rodent repair deficiency, complementation group 210090MGI:95413Inparanoid, OMA, EggNOG
Rat308415Ercc2ERCC excision repair 2, TFIIH core complex helicase subunit10116RGD:1309109Inparanoid, OMA, EggNOG
Dog493995ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit9615VGNC:40442Inparanoid, OMA, EggNOG
Cow100125238ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit9913VGNC:28569Inparanoid, OMA, EggNOG
Opossum100012006ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit13616Inparanoid, OMA, EggNOG
Xenopusercc2excision repair cross-complementation group 2 [Source:Xenbase;Acc:XB-GENE-949792]8364OMA, EggNOG
Zebrafish393900ercc2excision repair cross-complementation group 27955ZDB-GENE-040426-997Inparanoid, OMA, EggNOG
Fruitfly37414XpdXeroderma pigmentosum D7227FBgn0261850Inparanoid, EggNOG
S.cerevisiae856918RAD3TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD34932S000000973Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    DNA binding protein    /    TFIIH basal transcription factor complex helicase XPD subunit
protein    /    nucleic acid binding    /    DNA helicase    /    TFIIH basal transcription factor complex helicase XPD subunit
protein    /    nucleic acid binding    /    helicase    /    TFIIH basal transcription factor complex helicase XPD subunit
DTO Classes
protein    /    Enzyme    /    Helicase    /    DNA helicase    /    TFIIH basal transcription factor complex helicase XPD subunit

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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