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SIRT2

DescriptionNAD-dependent protein deacetylase sirtuin-2

Gene and Protein Information

Gene ID22933
Uniprot Accession IDs Q8IXJ6 A8K3V1 B2RB45 O95889 Q924Y7 Q9P0G8 Q9UNT0 Q9Y6E9 U5TP13
Ensembl ID ENSP00000249396
Symbol SIR2L SIR2L2 SIR2 SIR2L SIR2L2
FamilyBelongs to the sirtuin family. Class I subfamily.
Sequence
MAEPDPSHPLETQAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp456013SIRT2sirtuin 29598VGNC:12099OMA, EggNOG
Macaque100425019SIRT2sirtuin 29544Inparanoid, OMA, EggNOG
Mouse64383Sirt2sirtuin 210090MGI:1927664Inparanoid, OMA, EggNOG
Rat361532Sirt2sirtuin 210116RGD:621481Inparanoid, OMA
Dog612558SIRT2sirtuin 29615VGNC:53983Inparanoid, OMA, EggNOG
Horse100146611SIRT2sirtuin 29796VGNC:22987Inparanoid, OMA, EggNOG
Cow504463SIRT2sirtuin 29913VGNC:34631Inparanoid, OMA, EggNOG
Pig100125964SIRT2sirtuin 29823OMA, EggNOG
Anole lizard100559366sirt2sirtuin 228377Inparanoid, OMA
Xenopus100489469sirt2sirtuin 28364XB-GENE-987375Inparanoid, OMA
Zebrafish322309sirt2sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)7955ZDB-GENE-030131-1028Inparanoid, OMA
S.cerevisiae856092HST2histone deacetylase HST24932S000005936Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    hydrolase    /    deacetylase    /    NAD-dependent protein deacetylase sirtuin-2
protein    /    hydrolase    /    chromatin/chromatin-binding protein    /    NAD-dependent protein deacetylase sirtuin-2
DTO Classes
protein    /    Epigenetic regulator    /    Eraser    /    Histone deacetylase    /    HDAC class III    /    NAD-dependent protein deacetylase sirtuin-2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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