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WRN

DescripciónWerner syndrome ATP-dependent helicase

Gene and Protein Information

Gene ID7486
Uniprot Accession IDs Q14191 A1KYY9
Ensembl ID ENSP00000298139
Symbol RECQ3 RECQL2 RECQ3 RECQL2 RECQL3
FamilyBelongs to the helicase family. RecQ subfamily.
Sequence
MSEKKLETTAQQRKCPEWMNVQNKRCAVEERKACVRKSVFEDDLPFLEFTGSIVYSYDASDCSFLSEDISMSLSDGDVVGFDMEWPPLYNRGKLGKVALIQLCVSESKCYLFHVSSMSVFPQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKLKNFVELTDVANKKLKCTETWSLNSLVKHLLGKQLLKDKSIRCSNWSKFPLTEDQKLYAATDAYAGFIIYRNLEILDDTVQRFAINKEEEILLSDMNKQLTSISEEVMDLAKHLPHAFSKLENPRRVSILLKDISENLYSLRRMIIGSTNIETELRPSNNLNLLSFEDSTTGGVQQKQIREHEVLIHVEDETWDPTLDHLAKHDGEDVLGNKVERKEDGFEDGVEDNKLKENMERACLMSLDITEHELQILEQQSQEEYLSDIAYKSTEHLSPNDNENDTSYVIESDEDLEMEMLKHLSPNDNENDTSYVIESDEDLEMEMLKSLENLNSGTVEPTHSKCLKMERNLGLPTKEEEEDDENEANEGEEDDDKDFLWPAPNEEQVTCLKMYFGHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGKIGLVISPLISLMEDQVLQLKMSNIPACFLGSAQSENVLTDIKLGKYRIVYVTPEYCSGNMGLLQQLEADIGITLIAVDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVALTATASSSIREDIVRCLNLRNPQITCTGFDRPNLYLEVRRKTGNILQDLQPFLVKTSSHWEFEGPTIIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSSRCRRQIILSHFEDKQVQKASLGIMGTEKCCDNCRSRLDHCYSMDDSEDTSWDFGPQAFKLLSAVDILGEKFGIGLPILFLRGSNSQRLADQYRRHSLFGTGKDQTESWWKAFSRQLITEGFLVEVSRYNKFMKICALTKKGRNWLHKANTESQSLILQANEELCPKKLLLPSSKTVSSGTKEHCYNQVPVELSTEKKSNLEKLYSYKPCDKISSGSNISKKSIMVQSPEKAYSSSQPVISAQEQETQIVLYGKLVEARQKHANKMDVPPAILATNKILVDMAKMRPTTVENVKRIDGVSEGKAAMLAPLLEVIKHFCQTNSVQTDLFSSTKPQEEQKTSLVAKNKICTLSQSMAITYSLFQEKKMPLKSIAESRILPLMTIGMHLSQAVKAGCPLDLERAGLTPEVQKIIADVIRNPPVNSDMSKISLIRMLVPENIDTYLIHMAIEILKHGPDSGLQPSCDVNKRRCFPGSEEICSSSKRSKEEVGINTETSSAERKRRLPVWFAKGSDTSKKLMDKTKRGGLFS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp472732WRNWerner syndrome RecQ like helicase9598VGNC:7604OMA, EggNOG
Macaque695678WRNWerner syndrome RecQ like helicase9544Inparanoid, OMA, EggNOG
Mouse22427WrnWerner syndrome RecQ like helicase10090MGI:109635Inparanoid, OMA, EggNOG
Rat290805WrnWerner syndrome RecQ like helicase10116RGD:1564788Inparanoid, OMA, EggNOG
Dog493997WRNWerner syndrome RecQ like helicase9615Inparanoid, OMA, EggNOG
Horse100062021WRNWerner syndrome RecQ like helicase9796Inparanoid, OMA, EggNOG
Cow505061WRNWerner syndrome RecQ like helicase9913Inparanoid, OMA, EggNOG
Pig100512139WRNWerner syndrome RecQ like helicase9823OMA, EggNOG
Opossum100019443WRNWerner syndrome RecQ like helicase13616Inparanoid, OMA, EggNOG
PlatypusWRNWerner syndrome RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:12791]9258OMA, EggNOG
Anole lizard100561844wrnWerner syndrome RecQ like helicase28377Inparanoid, OMA, EggNOG
Xenopus734043wrnWerner syndrome, RecQ helicase-like8364XB-GENE-992875Inparanoid, OMA, EggNOG
Zebrafish569495wrnWerner syndrome7955ZDB-GENE-070702-2Inparanoid, OMA
C. elegans174081wrn-1Probable Werner syndrome ATP-dependent helicase homolog 16239Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    DNA binding protein    /    Werner syndrome ATP-dependent helicase
protein    /    nucleic acid binding    /    DNA helicase    /    Werner syndrome ATP-dependent helicase
protein    /    nucleic acid binding    /    helicase    /    Werner syndrome ATP-dependent helicase
DTO Classes
protein    /    Enzyme    /    Helicase    /    DNA helicase    /    Werner syndrome ATP-dependent helicase

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

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