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TOP1

DescripciónDNA topoisomerase 1

Gene and Protein Information

Gene ID7150
Uniprot Accession IDs P11387 A8KA78 E1P5W3 O43256 Q12855 Q12856 Q15610 Q5TFY3 Q9UJN0
Ensembl ID ENSP00000354522
Symbol TOPI
FamilyBelongs to the type IB topoisomerase family.
Sequence
MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp458252TOP1DNA topoisomerase I9598VGNC:10014OMA, EggNOG
Macaque697300TOP1DNA topoisomerase I9544Inparanoid, OMA, EggNOG
Mouse21969Top1topoisomerase (DNA) I10090MGI:98788Inparanoid, OMA, EggNOG
Rat64550Top1DNA topoisomerase I10116RGD:621246Inparanoid, OMA
Dog477229TOP1DNA topoisomerase I9615VGNC:49631Inparanoid, OMA, EggNOG
Horse100070532TOP1DNA topoisomerase I9796VGNC:50515Inparanoid, OMA, EggNOG
Cow534799TOP1DNA topoisomerase I9913VGNC:49136Inparanoid, OMA, EggNOG
Pig100518587TOP1DNA topoisomerase I9823Inparanoid, OMA, EggNOG
Opossum100032710TOP1DNA topoisomerase I13616Inparanoid, EggNOG
Platypus100078817TOP1DNA topoisomerase I9258Inparanoid, OMA, EggNOG
Chicken396004TOP1topoisomerase (DNA) I9031CGNC:2691Inparanoid, OMA, EggNOG
Anole lizard100559150top1DNA topoisomerase I28377Inparanoid, OMA, EggNOG
Xenopus100496521top1.1DNA topoisomerase I, gene 18364XB-GENE-950002Inparanoid, EggNOG
Zebrafish553496top1lDNA topoisomerase I, like7955ZDB-GENE-060616-217Inparanoid, OMA, EggNOG
Fruitfly32458Top1Topoisomerase 17227FBgn0004924Inparanoid, EggNOG
S.cerevisiae854156TOP1DNA topoisomerase 14932S000005366OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    DNA topoisomerase    /    DNA topoisomerase 1
DTO Classes
protein    /    Enzyme    /    Isomerase    /    DNA topoisomerase    /    DNA topoisomerase 1

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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