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PLK4

DescripciónSerine/threonine-protein kinase PLK4

Gene and Protein Information

Gene ID10733
Uniprot Accession IDs O00444 B2RAL0 B7Z837 B7Z8G7 Q8IYF0 Q96Q95 Q9UD84 Q9UDE2
Ensembl ID ENSP00000270861
Symbol SAK STK18 SAK STK18 MCCRP2
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
Sequence
MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp461480PLK4polo like kinase 49598VGNC:7051OMA, EggNOG
Macaque710233PLK4polo like kinase 49544Inparanoid, OMA, EggNOG
Mouse20873Plk4polo like kinase 410090MGI:101783Inparanoid, OMA, EggNOG
Rat310344Plk4polo-like kinase 410116RGD:1305390Inparanoid, OMA, EggNOG
Dog476087PLK4polo like kinase 49615VGNC:44698Inparanoid, OMA, EggNOG
Horse100063593PLK4polo like kinase 49796VGNC:21582Inparanoid, OMA, EggNOG
Cow514405PLK4polo like kinase 49913VGNC:33036Inparanoid, OMA, EggNOG
Opossum100010836PLK4polo like kinase 413616Inparanoid, OMA, EggNOG
Chicken422497PLK4polo like kinase 49031CGNC:51756OMA, EggNOG
Anole lizard100557501plk4polo like kinase 428377Inparanoid, OMA, EggNOG
Xenopus100038180plk4polo like kinase 48364XB-GENE-493608Inparanoid, OMA, EggNOG
Zebrafish368390plk4polo-like kinase 4 (Drosophila)7955ZDB-GENE-030619-14Inparanoid, OMA, EggNOG
Fruitfly40384SAKSak kinase7227FBgn0026371Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    PLK family    /    Serine/threonine-protein kinase plk4

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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