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ERBB2

DescripciónReceptor tyrosine-protein kinase erbB-2

Gene and Protein Information

Gene ID2064
Uniprot Accession IDs P04626 B2RZG3 B4DHN3 Q14256 Q6LDV1 Q9UMK4 X5D2V5
Ensembl ID ENSP00000269571
Symbol HER2 MLN19 NEU NGL NEU NGL HER2 TKR1 CD340 HER-2 MLN 19 HER-2/neu
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
Sequence
MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp454636ERBB2erb-b2 receptor tyrosine kinase 29598VGNC:9276OMA, EggNOG
Macaque697573ERBB2erb-b2 receptor tyrosine kinase 29544Inparanoid, OMA, EggNOG
Mouse13866Erbb2erb-b2 receptor tyrosine kinase 210090MGI:95410Inparanoid, OMA, EggNOG
Rat24337Erbb2erb-b2 receptor tyrosine kinase 210116RGD:2561Inparanoid, OMA, EggNOG
Dog403883ERBB2erb-b2 receptor tyrosine kinase 29615VGNC:40436Inparanoid, OMA, EggNOG
Horse100054739ERBB2erb-b2 receptor tyrosine kinase 29796VGNC:17649Inparanoid, OMA, EggNOG
Cow505709ERBB2erb-b2 receptor tyrosine kinase 29913VGNC:28563OMA, EggNOG
Pig100516641ERBB2erb-b2 receptor tyrosine kinase 29823OMA, EggNOG
Opossum100017172ERBB2erb-b2 receptor tyrosine kinase 213616Inparanoid, OMA, EggNOG
Anole lizard100565910erbb2erb-b2 receptor tyrosine kinase 228377Inparanoid, OMA
Zebrafish386966erbb2erb-b2 receptor tyrosine kinase 27955ZDB-GENE-031118-121Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    EGFR family    /    Receptor tyrosine-protein kinase erbb-2

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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