Tauroursodeoxycholate dihydrate - Moligand™, 10 mM in DMSO , CAS No.117609-50-4

CAS: 117609-50-4 Cat. No.: T1498916 Peso molecular: 535.7 PubChem CID: 71306862
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
T1498916-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
69,90US$
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Tauroursodeoxycholate (Tauroursodeoxycholic acid; TDUCA) dihydrate is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12 . Tauroursodeoxycholate also inhibits ERK .

Specifications

Especificaciones y pureza
Moligand™, 10 mM in DMSO
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Nombres e identificadores
Isómeros SMILES C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.O.O
CAS alternativo 14605-22-2
PubChem CID 71306862
Peso molecular 535.7

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Citations of This Product
Referencias
1. Xi Chen, Long-Yun Li, Jin-Lan Jiang, Kai Li, Zhen-Bo Su, Fu-Qiang Zhang, Wen-Jing Zhang, Guo-Qing Zhao.  (2018)  Propofol elicits autophagy via endoplasmic reticulum stress and calcium exchange in C2C12 myoblast cell line.  PLoS One,  13  (5): (e0197934).  [PMID:29795639] [10.1371/journal.pone.0197934]
2. Qian Fang, Xiaoying Hou, Limei Fan, Yufei Deng, Xiaoxuan Li, Hongyun Zhang, Haiping Wang, Zhengqi Fu, Binlian Sun, Xiji Shu, Hongzhi Du, Yuchen Liu.  (2025)  Gut microbiota derived DCA enhances FOLFOX efficacy via Ugt1a6b mediated enterohepatic circulation in colon cancer.  PHARMACOLOGICAL RESEARCH,      [PMID:39894186] [10.1016/j.phrs.2025.107636]
3. Yilong Liu, Ruoqi Wang, Jinren Zhou, Qiang Lyu, Xiaoyong Zhao, Xiaochun Yang, Kunsong Chen, Zhiwei Gao, Xian Li.  (2025)  Myricetin alleviates high-fat diet-induced atherosclerosis in ApoE−/− mice by regulating bile acid metabolism involved in gut microbiota remodeling.  Food & Function,      [PMID:40059779] [10.1039/D5FO00374A]
4. Wen Ma, Mingxia Liu, Mengling Tu, Gang Wang, Jun Li, Fen Liu, Jian Yang, Xianjiang Li.  (2024)  Novel multi-layered MXene as laser desorption ionization mass spectrometry matrix for rapid detection of small biomolecules.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.157466]
5. Guang Chen, Gang Yu, Zheng Yong, Hui Yan, Ruibin Su, Huijun Wang.  (2021)  A large dose of methamphetamine inhibits drug‑evoked synaptic plasticity via ER stress in the hippocampus.  Molecular Medicine Reports,  23  (4): (1-1).  [PMID:33576466] [10.3892/mmr.2021.11917]
6. Lin Xu, Yuanyuan Zhao, Yang Yang, Enbo Qi, Boao Liu, Peili Zhuang, Shiyi Song, Tingmin Chang, Zhiguo Chen, Xiaohong Kang, Xiwen Xiong.  (2025)  Constitutive hepatic mTORC1 activation aggravates alcohol-induced liver injury via endoplasmic reticulum stress-mediated ferroptosis.  AMERICAN JOURNAL OF PATHOLOGY,      [PMID:40204188] [10.1016/j.ajpath.2025.03.005]
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