Tazobactam Sodium Salt - ≥90% , CAS No.89785-84-2

CAS: 89785-84-2 Cat. No.: T141429 Peso molecular: 322.27 Número EC: 685-629-4 PubChem CID: 23663400

GRADE & PURITY ≥90%

Synonyms

Tazobactam sodium | Sodium (2S,3S,5R)-3-[(1H-1,2,3-Triazol-1-yl)methyl]-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

Storage

Room temperature

Shipped In

Normal

Descripción general

Tazobactam sodium is a LACTB (β-lactamase) inhibitor and antibacterial.
A β-lactamase inhibitor and antibacterial agent

Specifications

Sinónimos

Tazobactam sodium | Sodium (2S, 3S, 5R)-3-[(1H-1, 2, 3-Triazol-1-yl)methyl]-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4, 4-dioxide

Especificaciones y pureza

≥90%

Mecanismos bioquímicos y fisiológicos

Tazobactam is a β -Lactamase inhibitor. When used with β-lactam antibiotics I, it enhances their effect.β-lactamase inhibitor. Antibiotic agent. Penicillin derivative. Broadens the spectrum of activity of piperacillin in vivo.

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥90%

Nombres e identificadores

• Pubchem Sid: 504769471
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504769471
• Sonrisas canónicas: CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+]
• IUPAC Name: sodium;(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• InChIKey: RFMIKMMOLPNEDG-QVUDESDKSA-M
• INCHI: 1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1
• Isómeros SMILES: C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+]
• PubChem CID: 23663400
• Peso molecular: 322.27

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Alpha amino acids and derivatives
• Alternative Parents: Penams Triazoles Thiazolidines Tertiary carboxylic acid amides Sulfones Heteroaromatic compounds Azetidines Carboxylic acid salts Azacyclic compounds Carboxylic acids Monocarboxylic acids and derivatives Hydrocarbon derivatives Organic zwitterions Organopnictogen compounds Organonitrogen compounds Carbonyl compounds Organic oxides Organic sodium salts
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Alpha-amino acid or derivatives - Penam - Azole - Beta-lactam - Sulfone - Heteroaromatic compound - Tertiary carboxylic acid amide - Thiazolidine - 1,2,3-triazole - Azetidine - Carboxamide group - Carboxylic acid salt - Lactam - Organic alkali metal salt - Azacycle - Organoheterocyclic compound - Carboxylic acid - Monocarboxylic acid or derivatives - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Organic oxide - Organic nitrogen compound - Carbonyl group - Organopnictogen compound - Organic sodium salt - Organic zwitterion - Organic salt - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.
• External Descriptors: organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

bla Beta-lactamase TEM (457 Activities)

Discover Target: bla

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ampC Beta-lactamase AmpC (62480 Activities)

Discover Target: ampC

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blaZ Beta-lactamase (285 Activities)

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Beta-lactamase class C (68 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Enterobacter cloacae (7976 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Escherichia coli (133304 Activities)

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Serratia marcescens (3237 Activities)

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Mus musculus (284745 Activities)

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Stenotrophomonas maltophilia (1743 Activities)

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ccrA Beta-lactamase type II (170 Activities)

Discover Target: ccrA

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Beta-lactamase L1 (242 Activities)

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Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in water (100 mg/ml), and methanol.
• Índice de refracción: 1.82
• Punto de ebullición (°C): 707.1° C
• Punto de fusión (°C): 140-147°C
• Peso molecular: 322.280 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 3
• Exact Mass: 322.035 Da
• Monoisotopic Mass: 322.035 Da
• Topological Polar Surface Area: 134.000 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 578.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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