TBK1-IN-1 - ≥98% , CAS No.T659201

CAS: T659201 Cat. No.: T659201 Peso molecular: 489.61

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

TBK1-IN-1 is a potent and selective TANK binding kinase 1 (TBK1) inhibitor with an IC 50 value of 22.4 nM. TBK1-IN-1 inhibits TBK1 downstream target genes cxcl10 and ifnβ expression. TBK1-IN-1 has anticancer activity.

Appearance:Solid

IC50& Target:TBK1 22.4 nM (IC 50 )

In Vitro:TBK1-IN-1 (compound 7l; 0.1 and 1 μM; 2 h) inhibitsTBK1 downstream target genes cxcl10 and ifnβ expression in THP1 and RAW264.7 cells induced by poly (I:C) and lipopolysaccharide, respectively. TBK1-IN-1 (1-100 μM; 72 h) has moderate antiproliferativ

Biological Activity:TBK1-IN-1 is a potent and selective TANK binding kinase 1 (TBK1) inhibitor with an IC 50 value of 22.4 nM. TBK1-IN-1 inhibits TBK1 downstream target genes cxcl10 and ifnβ expression. TBK1-IN-1 has anticancer activity.

Specifications

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: CC(N1CCN(CC1)CC2=CC=CC(NC3=NC=C4C=CN(C4=N3)CCCNC(C5CCC5)=O)=C2)=O
• Peso molecular: 489.61