Teicoplanin - Moligand™, ≥900ug/mg , CAS No.61036-62-2

CAS: 61036-62-2 Cat. No.: T304131 Peso molecular: 1900

GRADE & PURITY Moligand™, ≥900ug/mg

Synonyms

Teichomycin

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Teicoplanin is a semisynthetic glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus faecalis.

Specifications

Sinónimos

Teichomycin

Especificaciones y pureza

Moligand™, ≥900ug/mg

Mecanismos bioquímicos y fisiológicos

Antibiotic. Active against Gram-positive bacteria. Able to inhibit cell wall biosynthesis.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Nombres e identificadores

• Sonrisas canónicas: CCCCCCCCCC(=O)NC1C(C(C(OC1OC2=C3C=C4C=C2OC5=C(C=C(C=C5)C(C6C(=O)NC(C7=C(C(=CC(=C7)O)OC8C(C(C(C(O8)CO)O)O)O)C9=C(C=CC(=C9)C(C(=O)N6)NC(=O)C4NC(=O)C1C2=CC(=CC(=C2)OC2=C(C=CC(=C2)C(C(=O)NC(CC2=CC(=C(O3)C=C2)Cl)C(=O)N1)N)O)O)O)C(=O)O)OC1C(C(C(C(O1)CO)O)O)NC(=O)C)Cl)CO)O)O
• IUPAC Name: (1S,2R,19R,22S,34S,37R,40R,52R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-22-amino-5,15-dichloro-64-[(2S,3R,4R,5S,6R)-3-(decanoylamino)-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-26,31,44,49-tetrahydroxy-21,35,38,54,56,59-hexaoxo-47-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7,13,28-trioxa-20,36,39,53,55,58-hexazaundecacyclo[38.14.2.23,6.214,17.219,34.18,12.123,27.129,33.141,45.010,37.046,51]hexahexaconta-3,5,8,10,12(64),14,16,23(61),24,26,29(60),30,32,41(57),42,44,46(51),47,49,62,65-henicosaene-52-carboxylic acid
• InChIKey: BJNLLBUOHPVGFT-VPMXZCLFSA-N
• INCHI: 1S/C88H97Cl2N9O33/c1-3-4-5-6-7-8-9-10-60(108)94-68-74(113)71(110)58(32-101)129-87(68)132-78-55-26-40-27-56(78)126-52-18-14-38(24-47(52)90)77(131-86-67(92-34(2)103)73(112)70(109)57(31-100)128-86)69-84(121)98-66(85(122)123)45-29-42(105)30-54(127-88-76(115)75(114)72(111)59(33-102)130-88)61(45)44-23-37(13-15-49(44)106)63(81(118)99-69)96-83(120)65(40)97-82(119)64-39-21-41(104)28-43(22-39)124-53-25-36(12-16-50(53)107)62(91)80(117)93-48(79(116)95-64)20-35-11-17-51(125-55)46(89)19-35/h11-19,21-30,48,57-59,62-77,86-88,100-102,104-107,109-115H,3-10,20,31-33,91H2,1-2H3,(H,92,103)(H,93,117)(H,94,108)(H,95,116)(H,96,120)(H,97,119)(H,98,121)(H,99,118)(H,122,123)/t48-,57-,58-,59-,62+,63-,64+,65-,66-,67-,68-,69+,70-,71-,72-,73-,74-,75+,76+,77-,86+,87+,88+/m1/s1
• Isómeros SMILES: CCCCCCCCCC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC2=C3C=C4C=C2OC5=C(C=C(C=C5)[C@H]([C@H]6C(=O)N[C@H](C7=C(C(=CC(=C7)O)O[C@@H]8[C@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C9=C(C=CC(=C9)[C@H](C(=O)N6)NC(=O)[C@@H]4NC(=O)[C@@H]1C2=CC(=CC(=C2)OC2=C(C=CC(=C2)[C@@H](C(=O)N[C@H](CC2=CC(=C(O3)C=C2)Cl)C(=O)N1)N)O)O)O)C(=O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)NC(=O)C)Cl)CO)O)O
• Peso molecular: 1900
• Reaxy-Rn: 25078866
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25078866&ln=

Propiedades químicas y físicas

• Solubilidad: H2O : 100 mg/mL (Need ultrasonic);DMSO : 100 mg/mL (Need ultrasonic)
• Sensibilidad: Heat sensitive
• Índice de refracción: 1.76

Referencias

1. Yechang Guo, Shaofeng Wang, Peiyue Li, Pan Zhang, Wei Wang.  (2023)  Rapid Colloidal Gold Immunoassay for Pharmacokinetic Evaluation of Vancomycin in the Cerebrospinal Fluid and Plasma of Beagle Dogs.  SENSORS,  23  (21): (8978).  [PMID:37960677] [10.3390/s23218978]

2. Lu Ye, Jiang Longlong, Yu Yang, Wang Dehua, Sun Wentao, Liu Yang, Yu Jing, Zhang Jun, Wang Kai, Hu Han, Wang Xiao, Ma Qingming, Wang Xiaoxiong.  (2022)  Liquid-liquid triboelectric nanogenerator based on the immiscible interface of an aqueous two-phase system.  Nature Communications,  13  (1): (1-12).  [PMID:36085155] [10.1038/s41467-022-33086-2]

3. Xianghai Zeng, Pengfei She, Linying Zhou, Shijia Li, Zubair Hussain, Lihua Chen, Yong Wu.  (2020)  Drug repurposing: Antimicrobial and antibiofilm effects of penfluridol against Enterococcus faecalis.  MicrobiologyOpen,  10  (1): (e1148).  [PMID:33345466] [10.1002/mbo3.1148]

4. Wenwen Cao, Anli Qin, Wenqian Zhu, Chaohai Pang, Zhongsheng Yi, Xionghui Ma, Shuhuai Li, Jianping Li.  (2024)  In Situ growth of high-crystallinity MOF@CTF core-shell hybrid heterostructures and their application in photoelectrochemical sensing of vancomycin.  Surfaces and Interfaces,      [PMID:] [10.1016/j.surfin.2024.104963]

5. Liufu Zhang, Jianwei Di, Haoyang Wang, Zhiwei Zhou, Yuxi Wang, Jun Long, Yanqiu Zhang, Jing Guo, Xu Jiang, Lu Shao.  (2025)  Tear-film-inspired interfacial polymerization engineering nanofiltration membrane architecture for highly efficient antibiotic desalination.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.164990]

6. Chen Huang, Ling-Jie Guo, Jia-Yi Li, Yue-Wen Chen, Bing Wu, Yi-Wei Liu, Chen-Zhi Zhang, Wei-Wei Lin, Ye Yang, Jin-Yuan Chen, Zhou-Jie Liu.  (2025)  A CRISPR-Cas12a Fluorescent Aptasensor for Point-of-Care Drug Concentration Detection: A Synergistic Regulation by DNA Aptamer and RNA Blocker.  ANALYTICAL CHEMISTRY,      [PMID:41144643] [10.1021/acs.analchem.5c03744]