Temoporfin - 10mM in DMSO , CAS No.122341-38-2

CAS: 122341-38-2 Cat. No.: T655635 Peso molecular: 680.75 Número EC: 624-374-5 PubChem CID: 60751

GRADE & PURITY 10mM in DMSO

Storage

Protected from light,Argon charged,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers .

In Vitro

A detailed confocal fluorescence microscopy study of a human adenocarcinoma shows weak localization of Temoporfin in lysosomes and mitochondria. Instead, it is found to be localized in the endoplasmic reticulum (ER) and the Golgi apparatus. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Temoporfin in liver tissue decreases rapidly in time after initial high levels at 4 h after administration (0.1-0.3 mg/kg). In tumour tissue no decrease in photosensitizer levels occurred, with Temoporfin remaining high up to 48 h after administration. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers.

Condiciones de almacenamiento de almacenamiento

Protected from light, Argon charged, Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Nombres e identificadores

• Isómeros SMILES: C1CC2=NC1=C(C3=CC=C(N3)C(=C4C=CC(=N4)C(=C5C=CC(=C2C6=CC(=CC=C6)O)N5)C7=CC(=CC=C7)O)C8=CC(=CC=C8)O)C9=CC(=CC=C9)O
• PubChem CID: 60751
• Peso molecular: 680.75