Tetracaine HCl - 10mM in DMSO , Sodium channel alpha subunit blocker, CAS No.136-47-0, Sodium channel alpha subunit blocker

CAS: 136-47-0 Cat. No.: T408312 Peso molecular: 300.82 Número EC: 205-248-5 PubChem CID: 8695

GRADE & PURITY 10mM in DMSO

Synonyms

Amethocalne HCl | 4-​(butylamino)​-​benzoic acid 2-​(dimethylamino)​ethyl ester, hydrochloride (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Tetracaine HCl Tetracaine HCl (Amethocalne) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

Amethocalne HCl | 4-​(butylamino)​-​benzoic acid 2-​(dimethylamino)​ethyl ester, hydrochloride (1:1)

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Tetracaine HCl (Amethocalne) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

BLOCKER

Mecanismo de acción

Sodium channel alpha subunit blocker

Nombres e identificadores

• Isómeros SMILES: CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C.Cl
• WGK Alemania: 3
• RTECS: DG4900000
• PubChem CID: 8695
• Número ONU: 2811
• Peso molecular: 300.82
• Reaxy-Rn: 3918400

Propiedades químicas y físicas

• Punto de fusión (°C): 149°C

Referencias

1. Zhanyi Yang, Shiqi He, Jiajun Wang, Yi Yang, Licong Zhang, Yanbing Li, Anshan Shan.  (2019)  Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens.  JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:30958004] [10.1021/acs.jmedchem.9b00149]

2. Xiaokang Guan, Qiao Lu, Xiangxu Zhao, Xiaowen Yan, Renato Zenobi.  (2023)  Spatio-Temporal Analysis of Anesthetics in Mice by Solid-Phase Microextraction: Dielectric Barrier Discharge Ionization Mass Spectrometry.  ANALYTICAL CHEMISTRY,      [PMID:37560898] [10.1021/acs.analchem.3c02123]

3. Kun Chen, Guixin Wang, Xuedong Wang, Huili Wang.  (2023)  A smartphone-based ratiometric fluoroprobe based on blue-red dual-emission signals of thiochrome and copper nanoclusters for sensitive assay of metam-sodium in cucumbers.  TALANTA,      [PMID:37207510] [10.1016/j.talanta.2023.124673]

4. Lin-Ping Xue, Hai-Song Feng.  (2025)  HMGB2 knockdown ameliorates retinal ganglion cell injury by inhibiting NLRP3 inflammasome activation after retinal ischemia.  International Journal of Ophthalmology,  18  (1): (39).  [PMID:39829613] [10.18240/ijo.2025.01.05]