Tetrahydrouridine (aqueous solution) - ≥95%, 100mM in water , CAS No.18771-50-1

CAS: 18771-50-1 Cat. No.: T275497 Peso molecular: 248.23 Número EC: 987-001-8 PubChem CID: 29243

GRADE & PURITY ≥95%, 100mM in water

Synonyms

1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one

Storage

Protected from light,Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.

Specifications

Sinónimos

1-[3, 4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1, 3-diazinan-2-one

Especificaciones y pureza

≥95%, 100mM in water

Mecanismos bioquímicos y fisiológicos

Competitive cytidine deaminase inhibitor (IC 50 = 152 μM). Uridine analog. Modulates antiproliferative effects. Orally active. Also available as a solid.

Condiciones de almacenamiento de almacenamiento

Protected from light, Desiccated, Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥95%

Nombres e identificadores

• Isómeros SMILES: C1CN(C(=O)NC1O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
• PubChem CID: 29243
• Peso molecular: 248.23

Objetivos asociados (humanos)

CDA Tclin Cytidine deaminase (3 Activities)

Discover Target: CDA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Solubilidad: Supplied in water (100 mM)
• Sensibilidad: air and light sensitive