Etilendiaminotetraacetato de tetrasodio tetrahidratado - ≥98%(T), used for EDTA is a metalloproteinase inhibitor with an effective concentration range of 1-10 mM. It serves as a chelating agent for zinc ions in the active site of metalloproteinases and ca

CAS: 13235-36-4 Cat. No.: T161517 Peso molecular: 452.23 Beilstein Registry Number: 4(4)2451 Número EC: 603-569-9 PubChem CID: 23287279

GRADE & PURITY ≥98%(T)

Synonyms

EDTA, Tetrasodium Tetrahydrate Salt | L13NHD21X6 | Edetate sodium tetrahydrate | ethylenediaminetetraacetic acid tetrasodium salt tetrahydrate

Storage

Room temperature

Shipped In

Normal

Descripción general

Soluble en agua a temperatura ambiente hasta 1,45 M. El pH de esta solución será aproximadamente de 10 a 11 y será bastante viscosa.
El EDTA es un inhibidor de las metaloproteasas, a concentraciones efectivas de 1-10 mM. El EDTA actúa como quelante del ion cinc en el sitio activo de las metaloproteasas, y también puede inhibir otras proteasas dependientes de iones metálicos, como las cisteína proteasas dependientes del calcio. Para su uso como anticoagulante, las sales disódicas o tripotásicas del EDTA son las más utilizadas. La concentración óptima es de 1,5 mg por ml de sangre.

Specifications

Sinónimos

EDTA, Tetrasodium Tetrahydrate Salt | L13NHD21X6 | Edetate sodium tetrahydrate | ethylenediaminetetraacetic acid tetrasodium salt tetrahydrate

Especificaciones y pureza

≥98%(T)

Aplicación

EDTA is a metalloproteinase inhibitor with an effective concentration range of 1-10 mM. It serves as a chelating agent for zinc ions in the active site of metalloproteinases and can also inhibit other metal-dependent proteases, such as calcium-dependent c

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Pureza

≥98%(T)

Nombres e identificadores

• Pubchem Sid: 488200307
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488200307
• Sonrisas canónicas: C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].O.O.O.O.[Na+].[Na+].[Na+].[Na+]
• IUPAC Name: tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate;tetrahydrate
• InChIKey: XFLNVMPCPRLYBE-UHFFFAOYSA-J
• INCHI: 1S/C10H16N2O8.4Na.4H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;4*1H2/q;4*+1;;;;/p-4
• Isómeros SMILES: C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].O.O.O.O.[Na+].[Na+].[Na+].[Na+]
• PubChem CID: 23287279
• Peso molecular: 452.23
• Beilstein: 4(4)2451
• Reaxy-Rn: 3828865

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Tetracarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Tetracarboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Tetracarboxylic acids and derivatives
• Alternative Parents: Alpha amino acids Trialkylamines Carboxylic acid salts Amino acids Carboxylic acids Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Tetracarboxylic acid or derivatives - Alpha-amino acid - Alpha-amino acid or derivatives - Amino acid or derivatives - Amino acid - Carboxylic acid salt - Tertiary amine - Tertiary aliphatic amine - Carboxylic acid - Organic alkali metal salt - Organic sodium salt - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Amine - Organic oxygen compound - Organic salt - Organic zwitterion - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as tetracarboxylic acids and derivatives. These are carboxylic acids containing exactly four carboxyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Peso molecular: 452.230 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 14
• Rotatable Bond Count: 7
• Exact Mass: 452.061 Da
• Monoisotopic Mass: 452.061 Da
• Topological Polar Surface Area: 171.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 293.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 9

XLogP3

Referencias

1. Songchen Xie, Ngie Hing Wong, Jaka Sunarso, Qiang Guo, Chunguang Hou, Zhiguang Pang, Yuelian Peng.  (2022)  Cleaning mechanism of gypsum scaling in hydrophobic porous membranes.  DESALINATION,      [PMID:] [10.1016/j.desal.2022.116237]

2. Xinyang Zhang, Zhendong Gan, Yanrui Wang, Xiaobin Tang, Guibai Li, Heng Liang.  (2022)  Effect of chemical cleaning on nanofiltration process in treating surface water.  Journal of Water Process Engineering,      [PMID:] [10.1016/j.jwpe.2022.103271]

3. Peng Wu, Yuan Xiong, Chen Lei, Yuan Li, Xiang Liu, Cheng Zhang, Yudie Sun, Jian Zhang, Chun-Sing Lee, Kui Zhang.  (2021)  Chemical analysis and identification the fluorophores of photoluminescent carbon dots beyond infrared and X-ray photoelectron energy spectra.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2021.109750]

4. Yuan Wei-Qiang, Zhou Shou-Quan, Jiang Yu-Yan, Li Hao-Hong, Zheng Hui-Dong.  (2020)  Organocatalyzed styrene epoxidation accelerated by continuous-flow reactor.  Journal of Flow Chemistry,  10  (1): (227-234).  [PMID:] [10.1007/s41981-019-00065-6]

5. Yaru Li, Xiaodong Li, Xiaohui Liu, Liping Zhu, Wenjun Zhang, Junfeng Fang.  (2016)  Realizing High Performance Inverted Organic Solar Cells via a Nonconjugated Electrolyte Cathode Interlayer.  Journal of Physical Chemistry C,      [PMID:] [10.1021/acs.jpcc.6b10558]

6. Xusheng Cheng, Tao Xuan, Haoran Hu, Jianchi Wang, Jiantao Zai, Liwei Wang.  (2025)  Thermodynamic descriptor-guided ligand screening enables dendrite-free zinc deposition in alkaline flow batteries.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40795687] [10.1016/j.jcis.2025.138637]

7. Shaoxian Song, Song Wu, Yating He, Yiwen Zhang, Guangyin Fan, Yan Long, Shuyan Song.  (2024)  Boron/nitrogen-trapping and regulative electronic states around Ru nanoparticles towards bifunctional hydrogen production.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:38865881] [10.1016/j.jcis.2024.06.058]

8. Tao Wu, Xuewen Gao, Jiaxing Feng, Yuan Jin, Zhengye Feng.  (2025)  Improved prediction of radionuclides sorption and diffusion in bentonite-sand mixtures using VAE-MTDL: Integrating XRF, XRD, and CEC data.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.119683]