GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥99%
Synonyms
SMR004702789 | TGX221 | MFCD11113209 | N-Phenyl-1-(ethylcarbamoyl-1)-ethylcarbamate, D isomer | PI 3-Kbeta Inhibitor VI, TGX-221 - CAS 663619-89-4 | SB19244 | TGX-221 | FT-0767048 | 6L28AW98TH | 7-methyl-2-morpholin-4-yl-9-(1-phenylaminoethyl)-pyrido[1,2-
Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Tgx-221 is a P110 β - specific inhibitor. The IC50 of tgx-221 is 5 nm in cell-free assay. The selectivity of tgx-221 on P110 β is 1000 times that on P110 α.
Specifications
Sinónimos
SMR004702789 | TGX221 | MFCD11113209 | N-Phenyl-1-(ethylcarbamoyl-1)-ethylcarbamate, D isomer | PI 3-Kbeta Inhibitor VI, TGX-221 - CAS 663619-89-4 | SB19244 | TGX-221 | FT-0767048 | 6L28AW98TH | 7-methyl-2-morpholin-4-yl-9-(1-phenylaminoethyl)-pyrido[1, 2-
Especificaciones y pureza
Moligand™, ≥99%
Mecanismos bioquímicos y fisiológicos
TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110β .
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Mecanismo de acción
Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta
Nota
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as pyridopyrimidines. These are compounds containing a pyridopyrimidine, which consists of a pyridine fused to a pyrimidine. Pyridine is 6-membered ring consisting of five carbon atoms and a nitrogen atom. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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