≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Thymoquinone (TQ), also known as 2-isopropyl-5-methyl-1, 4-benzoquinone, is present in a crystalline triclinic form. It is the bioactive constituent of the volatile oil of black seed. TQ exhibits anti-inflammatory, antioxidant and anti-neoplastic effects both in vitro and in vivo. Thymoquinone has been used as an inhibitor of Escherichia coli ATP synthase and cell growth. It is also used as a drug against lower limb ischemia-reperfusion injury of sciatic nerve and femoral muscle.
This compound belongs to the class of organic compounds known as p-benzoquinones. These are benzoquinones where the two C=O groups are attached at the 1- and 4-positions, respectively.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Jing-Jing Liu, Zhan-Yi Wang, Bin-Bin Jiang, Shu-Qin Gao, Ying-Wu Lin. (2023) Protective effect of thymoquinone on glycation of human myoglobin induced by d-ribose. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:37741485][10.1016/j.ijbiomac.2023.127016]
2.Feixu Mo, Xianfeng Hu, Yi Ding, Rongyu Li, Youhua Long, Xiaomao Wu, Ming Li. (2021) Naturally produced magnolol can significantly damage the plasma membrane of Rhizoctonia solani. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, [PMID:34446208][10.1016/j.pestbp.2021.104942]
3.Xu Huan, Liu Bing, Xiao Zhen, Zhou Meiling, Ge Lin, Jia Fan, Liu Yanling, Jin Hongshan, Zhu Xiuliang, Gao Jian, Akhtar Javed, Xiang Bai, Tan Ke, Wang Guanyu. (2021) Computational and Experimental Studies Reveal That Thymoquinone Blocks the Entry of Coronaviruses Into In Vitro Cells. Infectious Diseases and Therapy, 10 (1):(483-494). [PMID:33532909][10.1007/s40121-021-00400-2]
4.Xiao Tu, Chenxi Duan, Siwei Wu, Shengli Fu, Jianmin Ye. (2021) Identification of plumbagin as an effective chemotherapeutic agent for treatment of Gyrodactylus infections. AQUACULTURE, [PMID:][10.1016/j.aquaculture.2021.736372]
5.Kaitong Jia, Lei Wu, Ziru Li, Tian Wei, Tingting Fan, Guiran Xiao. (2025) Thymoquinone Ameliorates Gut Epithelial Injury by Suppressing the JNK Signaling Pathway Based on Its Anti-Oxidant Property. Food Science & Nutrition, 13 (4):(e70113). [PMID:40129997][10.1002/fsn3.70113]
6.Wei-Wei Zheng, Jia-Xuan Ding, Yang-Xin Liang, Ling Ye. (2025) Hydroxypropyl‑β‑cyclodextrin/thymoquinone inclusion complex inhibits non‑small cell lung cancer progression through NF‑κB‑mediated ferroptosis. ONCOLOGY REPORTS, 54 (6):(1-14). [PMID:40970359][10.3892/or.2025.8990]
7.Jing-Jing Liu, Si-Dian Miao, Zhan-Yi Wang, Ya-Han Zhu, Bin-Bin Jiang, Shuang-Shuang Long, Shu-Qin Gao, Ying-Wu Lin. (2026) Inhibition of d-ribose-induced glycation of metalloprotein human myoglobin by bioactive quinones. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:][10.1016/j.saa.2026.127817]
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