Determine the necessary mass, volume, or concentration for preparing a solution.
TMC647055 Choline salt - ≥99% , CAS No.T658919
Disponible para pedir
GRADE & PURITY ≥99%
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
224,000+ productos de investigación · Triple ISO certified · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items
Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
TMC647055 (Choline salt) is a potent nonnucleoside NS5B polymerase inhibitor of HCV replication . TMC647055 Choline salt has potent HCV combine activity with an IC 50 value of 82 nM. TMC647055 Choline salt can be used for the research of Hepatitis C virus
Appearance:Solid
IC50& Target:EC90: 0.3 μM (Huh7-Luc cell) . EC50: 82 nM (HCV)
In Vitro:TMC647055 (Choline salt) has antiviral activity with an EC 90 value of 0.3 μM in Huh7-Luc cells. TMC647055 Choline salt has potent combine activity with an EC 50 value of 82 nM in cellular HCV assays. MCE has not independently confirmed the accu
In Vivo:TMC647055 Choline salt (compound 18a) (2mg/kg, iv.; 1mg/kg, po.) shows an acceptable PK profile, characterized by high oral bioavailability and high systemic exposure after single oral dosing of 10mg/kg, combined with a moderate plasma clearanceand low
Biological Activity:TMC647055 (Choline salt) is a potent nonnucleoside NS5B polymerase inhibitor of HCV replication . TMC647055 Choline salt has potent HCV combine activity with an IC 50 value of 82 nM. TMC647055 Choline salt can be used for the research of Hepatitis C virus
Specifications
Especificaciones y pureza
≥99%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Desiccated
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥99%
Nombres e identificadores
| Sonrisas canónicas | OCC[N+](C)(C)C.COC1=CC2=C(C=C1)C3=C(C4CCCCC4)C5=CC=C(C6=O)C=C5N3CC(C(N(C)CCOCCN(S(N6)(=O)=O)C)=O)=C2.[OH-] |
|---|---|
| Peso molecular | 727.91 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | DMSO : 62.5 mg/mL (85.86 mM; ultrasonic and warming and heat to 60°C) |
|---|
Citations of This Product
Referencias
| 1. Xiao Shujuan, Lu Xiaohui, Liu Hui, Gu Jiantao, Yu Shouwu, Tan Xiaoyao. (2022) High-flux nanofiltration membrane with modified highly dispersed MOF particles as nano filler. WATER SCIENCE AND TECHNOLOGY, 86 (10): (2642-2657). [PMID:] [10.2166/wst.2022.357] |
Calculadoras de soluciones
Reseñas
Reseñas de cliente
Remind me later
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.