Toluidine bule - Biological stain , CAS No.6586-04-5

CAS: 6586-04-5 Cat. No.: T104232 Peso molecular: 373.97 Beilstein Registry Number: 4068052 PubChem CID: 11456928
Disponible para pedir
GRADE & PURITY Biological Stain ? Biological stain grade — dyes characterized for staining cells and tissues. Use in histology and microscopy where staining consistency matters.
Synonyms
(7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium;dichlorozinc;dichloride | DTXSID00466405 | SBB058282 | Toluidine Blue, for microscopy (Hist., Vit.) | AKOS024375442
Storage
Desiccated,Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1g
T104232-1g
3
9,90US$
5g
T104232-5g
8
23,90US$
25g
T104232-25g
3
81,90US$
100g
T104232-100g
6
207,90US$
500g
T104232-500g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
999,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Biological stain Biological Stain for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Desiccated,Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Toluidine Blue is a basic thiazine metachromatic dye, which is used for selectively staining acidic tissue components such as carboxylates, sulfates, and phosphate radicals. It is found to have affinity for nucleic acids, and therefore binds to nuclear material of tissues with a high DNA and RNA content

Application:

Toluidine Blue is suitable for use in the following applications:
to demonstrate amyloid; DNA in plant material, mast cells, Nissl substance, nuclei, and sulfatides
in metachromatic staining of sulfated mucins and related materials
as staining agent to identify the development and accumulation of the cartilage matrix, proteoglycans for isolation and culture of mesenchymal stem cells from mouse compact bone.
staining of mucins in water-miscible resins and of nucleic acids in epoxy resins(1)

Specifications

Sinónimos
(7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium;dichlorozinc;dichloride | DTXSID00466405 | SBB058282 | Toluidine Blue, for microscopy (Hist., Vit.) | AKOS024375442
Especificaciones y pureza
Biological stain
Mecanismos bioquímicos y fisiológicos
Toluidine Blue is a basic thiazine metachromatic dye, which is used for selectively staining acidic tissue components such as carboxylates, sulfates, and phosphate radicals.It is found to have an affinity for nucleic acids and therefore binds to the nucle
Condiciones de almacenamiento de almacenamiento
Desiccated, Room temperature
Enviado en
Normal
Grado
Biological Stain
Nombres e identificadores
Pubchem Sid488197521
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488197521
Sonrisas canónicasCC1=CC2=C(C=C1N)SC3=CC(=[N+](C)C)C=CC3=N2.CC1=CC2=C(C=C1N)SC3=CC(=[N+](C)C)C=CC3=N2.[Cl-].[Cl-].Cl[Zn]Cl
IUPAC Name(7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium;dichlorozinc;dichloride
InChIKeyDAQXTSXITPUGRG-UHFFFAOYSA-L
INCHI1S/2C15H15N3S.4ClH.Zn/c2*1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13;;;;;/h2*4-8,16H,1-3H3;4*1H;/q;;;;;;+2/p-2
Isómeros SMILES CC1=CC2=C(C=C1N)SC3=CC(=[N+](C)C)C=CC3=N2.CC1=CC2=C(C=C1N)SC3=CC(=[N+](C)C)C=CC3=N2.[Cl-].[Cl-].Cl[Zn]Cl
WGK Alemania 3
PubChem CID 11456928
Peso molecular 373.97
Beilstein 4068052

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

39 results found

Lot NumberCertificate TypeFechaArticulo
L2212372Certificate of AnalysisJun 09, 2026 T104232
L2212370Certificate of AnalysisJun 09, 2026 T104232
F2605497Certificate of AnalysisMay 27, 2026 T104232
F2605478Certificate of AnalysisMay 27, 2026 T104232
F2605477Certificate of AnalysisMay 27, 2026 T104232
F2605476Certificate of AnalysisMay 27, 2026 T104232
F2605475Certificate of AnalysisMay 27, 2026 T104232
D2602034Certificate of AnalysisApr 15, 2026 T104232
E2409028Certificate of AnalysisFeb 05, 2026 T104232
F2225593Certificate of AnalysisDec 10, 2025 T104232
A2405268Certificate of AnalysisOct 11, 2025 T104232
A2405269Certificate of AnalysisOct 11, 2025 T104232
A2405267Certificate of AnalysisOct 11, 2025 T104232
G2509252Certificate of AnalysisJun 25, 2025 T104232
G2509251Certificate of AnalysisJun 25, 2025 T104232
G2509250Certificate of AnalysisJun 25, 2025 T104232
A2629061Certificate of AnalysisJun 25, 2025 T104232
L2424351Certificate of AnalysisDec 04, 2024 T104232
L2424350Certificate of AnalysisDec 04, 2024 T104232
C2511157Certificate of AnalysisDec 04, 2024 T104232
B2314069Certificate of AnalysisNov 11, 2024 T104232
B2314083Certificate of AnalysisNov 11, 2024 T104232
B2314080Certificate of AnalysisNov 11, 2024 T104232
L2212371Certificate of AnalysisSep 19, 2024 T104232
I2216602Certificate of AnalysisJun 20, 2024 T104232
F2419335Certificate of AnalysisJun 05, 2024 T104232
F2419334Certificate of AnalysisJun 05, 2024 T104232
H2106647Certificate of AnalysisMay 10, 2023 T104232
L2212373Certificate of AnalysisNov 03, 2022 T104232
K2328094Certificate of AnalysisNov 03, 2022 T104232
L2212367Certificate of AnalysisNov 03, 2022 T104232
L2212368Certificate of AnalysisNov 03, 2022 T104232
H2301095Certificate of AnalysisAug 19, 2022 T104232
I2216624Certificate of AnalysisAug 19, 2022 T104232
I2216601Certificate of AnalysisAug 19, 2022 T104232
I2216600Certificate of AnalysisAug 19, 2022 T104232
H2301088Certificate of AnalysisAug 19, 2022 T104232
F2225592Certificate of AnalysisMay 28, 2022 T104232
F2225546Certificate of AnalysisMay 28, 2022 T104232

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Propiedades químicas y físicas
SolubilidadSolubility: Soluble in water
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Wang Pei, Zhang MengYi, Qu JieHao, Wang LuJie, Geng JunZhao, Fu FeiYa, Liu XiangDong.  (2022)  Antibacterial cotton fabric prepared by a “grafting to” strategy using a QAC copolymer.  CELLULOSE,  29  (6): (3569-3581).  [PMID:] [10.1007/s10570-022-04469-x]
2. Anqi Wang, Wei Chen, Hang Xu, Zongli Xie, Xiaoying Zheng, Mingxiang Liu, Yueting Wang, Nannan Geng, Xiaoying Mu, Mingmei Ding.  (2022)  Heterostructured MoS2 quantum dot/GO lamellar membrane with improved transport efficiency for organic solvents inspired by the Namib Desert beetle.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2022.120402]
3. Jiangya Ma, Xue Fu, Wei Xia, Kun Fu, Yi Liao.  (2019)  Flocculation of a High-Turbidity Kaolin Suspension Using Hydrophobic Modified Quaternary Ammonium Salt Polyacrylamide.  Processes,  (2): (108).  [PMID:] [10.3390/pr7020108]
4. Xiu-Fang Yan, Zeng-Ping Chen, Yin-Yin Cui, Yuan-Liang Hu, Ru-Qin Yu.  (2016)  Quantitative generalized ratiometric fluorescence spectroscopy for turbid media based on probe encapsulated by biologically localized embedding.  ANALYTICA CHIMICA ACTA,      [PMID:27126788] [10.1016/j.aca.2016.03.033]
5. Zhihao Liu, Tingting Yang, Yuwen Yan, Yongtao Tang, Jianxin Meng, Fengyu Li.  (2024)  Self-calibrating colorimetric sensor assisted deep learning strategy for efficient and precise Fe(II) detection.  Surfaces and Interfaces,      [PMID:] [10.1016/j.surfin.2024.104389]
6. Ximing Zhong, Shunfeng Hu, Lingfeng Li, Xizhi Zhang, Guowei Liang, Dengle Duan, Hongjun Zhou, Xinhua Zhou.  (2025)  A novel biopolymer-based omniphobic coating system functionalized by polysilazane for anti-smudge, chemical shielding, and bacterial anti-adhesion applications.  Journal of Materials Chemistry A,      [PMID:] [10.1039/D5TA00581G]
7. Fu Dan, Li Ziyou, Feng Huafeng, Fan Fangling, Zhang Wang, He Liang.  (2025)  Chaperone mediated autophagy modulates microglia polarization and inflammation via LAMP2A in ischemia induced spinal cord injury.  Toxicology Research,  14  (2):   [PMID:40309223] [10.1093/toxres/tfaf061]
8. Yunsheng Shang, Xue Zhang, Xuemei Wang, Jin Yang, Xinxin Shi, Lu-Lu Qu, Yingqiu Gu.  (2025)  Au@Fe2O3 nanoflowers as highly sensitive SERS substrates to detect organic pollutants in water.  Materials Science and Engineering B-Advanced Functional Solid-State Materials,      [PMID:] [10.1016/j.mseb.2025.118396]
9. Jundong Zhu, Fan Yang, Chongwen Jiang, Zhonghua Li, Yanfang Zhou, Xin Li.  (2025)  Multifunctional Superhydrophobic Sponge In Situ Anchoring of Ag-MnO2 via Polydopamine Activation for Efficient Oil–Water Separation, Photothermal Conversion and Antibacterial Applications.  ACS Applied Materials & Interfaces,      [PMID:40328744] [10.1021/acsami.5c04476]
10. Mingdi Shi, You Pan, Haixiao Cao, Yongxin Guo, Xue Sun, Yuan Fu, Yihang Wu, Yufei Luo, Yangyu Lu, Zhenting Wu, Liang Jiang, Bo Li, Shichao Niu, Zhiwu Han.  (2025)  Bioinspired structural laminates with superior ice-repellence and damage resistance for aviation applications.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.163753]
11. Bolin Deng, Mi Zhou, Xiang Li, Jiayu Tong, Yuhua Gao, Tao Sun, Pengcheng Liu, Yingjie Zhang, Dalong Li, Xiquan Cheng.  (2025)  Developing regenerable levodopa/ε-polylysine magnetic nanoparticles for rapid selective adsorption of anionic dyes.  CHEMICAL ENGINEERING RESEARCH & DESIGN,      [PMID:] [10.1016/j.cherd.2025.05.042]
12. Zhanlin Zhang, Kun Wei, Jie Meng, Junwu Wei, Yupeng Su, Huan Tan, Xiaohong Li.  (2025)  Piezoelectric Amplification of Cascade Enzymatic Catalysis and Nanomotor Propulsion for Synergistic Electrodynamic-Starvation Tumor Therapy.  Advanced Healthcare Materials,      [PMID:40364626] [10.1002/adhm.202501280]
13. Yuanlin Wang, Yaqian Han, Jingshi Li, Zhaotong Wang, Kai Li, Tiancheng Bai, Lei Wang, Ye Sun, Chunying Chen, Miao Yu.  (2025)  Cell-specific ferroptosis targeting tumors while sparing immune cells.  BIOMATERIALS,      [PMID:40460787] [10.1016/j.biomaterials.2025.123457]
14. Zhu‐chen Zhou, Meng‐ting Liu, Yi‐jia Fangma, Bing‐jie Wan, Jing Zhou, Xiao‐lan Zhang, Yu‐ting Yan, Shu‐hui Deng, Yan Zhang, Yuan‐jie Zhang, Wen‐lu Li, Zhong Chen, Yan‐rong Zheng.  (2026)  Peiminine‐Induced Selective Autophagy of AIM2 Inflammasomes Rescues Cerebral Ischemic Injury.  Journal of the American Heart Association,  15  (3):   [PMID:41614275] [10.1161/JAHA.125.043374]
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