The store will not work correctly when cookies are disabled.
Parece que JavaScript está deshabilitado en su navegador. Para obtener la mejor experiencia en nuestro sitio, asegúrese de activar Javascript en su navegador.
· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items Topiroxostat - Moligand™, 10mM in DMSO , Xanthine dehydrogenase inhibitor, CAS No.577778-58-6, Xanthine dehydrogenase inhibitor
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)picolinonitrile | 2-Pyridinecarbonitrile, 4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]- | AKOS026750465 | UBVZQGOVTLIHLH-UHFFFAOYSA-N | FYX 051 | GTPL10592 | 4-[5-PYRIDIN-4-YL-1H-[1,2,4]TRIAZOL-3-YL]-PYRIDINE-2-CARBO
Shipped In
Dry ice packs + Cold packs
🧪
Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
📋
Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general Topiroxostat is a xanthine oxidoreductase (XOR) inhibitor。Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%).
Specifications Sinónimos
4-(5-(pyridin-4-yl)-1H-1, 2, 4-triazol-3-yl)picolinonitrile | 2-Pyridinecarbonitrile, 4-[5-(4-pyridinyl)-1H-1, 2, 4-triazol-3-yl]- | AKOS026750465 | UBVZQGOVTLIHLH-UHFFFAOYSA-N | FYX 051 | GTPL10592 | 4-[5-PYRIDIN-4-YL-1H-[1, 2, 4]TRIAZOL-3-YL]-PYRIDINE-2-CARBO
Especificaciones y pureza
Moligand™, 10mM in DMSO
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Mecanismo de acción
Xanthine dehydrogenase inhibitor
Propiedades del producto Nombres e identificadores Pubchem Sid 528767518 Sonrisas canónicas C1=CN=CC=C1C2=NC(=NN2)C3=CC(=NC=C3)C#N IUPAC Name 4-(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile InChIKey UBVZQGOVTLIHLH-UHFFFAOYSA-N INCHI 1S/C13H8N6/c14-8-11-7-10(3-6-16-11)13-17-12(18-19-13)9-1-4-15-5-2-9/h1-7H,(H,17,18,19) Isómeros SMILES C1=CN=CC=C1C2=NC(=NN2)C3=CC(=NC=C3)C#N CAS alternativo 577778-58-6 PubChem CID 5288320 Términos de entrada MeSH 4-(5-pyridin-4-yl-1H-(1,2,4) triazol-3-yl)pyridine-2-carbonitrile;FYX-051;topiroxostat Peso molecular 248.24
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Pyridines and derivatives Subclass Pyridyltriazoles Intermediate Tree Nodes Not available Direct Parent Pyridyl-1,2,4-triazoles Alternative Parents Triazoles Heteroaromatic compounds Nitriles Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Pyridyl-1,2,4-triazole - Heteroaromatic compound - 1,2,4-triazole - Triazole - Azole - Azacycle - Nitrile - Carbonitrile - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteromonocyclic compound Descripción This compound belongs to the class of organic compounds known as pyridyl-1,2,4-triazoles. These are organic compounds containing a pyridine ring attached to a 1,2,4-triazole ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Peso molecular 248.240 g/mol XLogP3 1.200 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 2 Exact Mass 248.081 Da Monoisotopic Mass 248.081 Da Topological Polar Surface Area 91.100 Ų Heavy Atom Count 19 Formal Charge 0 Complexity 344.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Citations of This Product Referencias 1. Jia-hong Liang, Xiao-lei Yi, Jia-min Gong, Zuo Du. (2024) Evaluation of the inhibitory effects of antigout drugs on human carboxylesterases in vitro. TOXICOLOGY IN VITRO, [PMID:38670244 ] [10.1016/j.tiv.2024.105833 ]
Calculadoras de soluciones Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator Reseñas Need help choosing the grade? Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our
Cookie Policy. Configuración Aceptar todo Rechazar
Shall we send you a message when we have discounts available?
Remind me later Permitir
Thank you! Please check your email inbox to confirm.
Oops! Notifications are disabled.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.
