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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items Tosedostat (CHR2797) - ≥95% , Aminopeptidase inhibitor, CAS No.238750-77-1, Aminopeptidase inhibitor
Synonyms
CHR-2797(Tosedostat) | Tosedostat | BCP9000524 | AC-375 | BENZENEACETIC ACID, .ALPHA.-(((2R)-2-((1S)-1-HYDROXY-2-(HYDROXYAMINO)-2-OXOETHYL)-4- METHYL-1-OXOPENTY)LAMINO)-, CYCLOPENTYL ESTER, (.ALPHA.S)- | Tosedostat [USAN:INN] | (5S,8S)-8-({(1R)-1-[3,5-bis
Shipped In
Ice chest + Ice pads
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Why this grade ≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
CHR-2797(Tosedostat) | Tosedostat | BCP9000524 | AC-375 | BENZENEACETIC ACID, .ALPHA.-(((2R)-2-((1S)-1-HYDROXY-2-(HYDROXYAMINO)-2-OXOETHYL)-4- METHYL-1-OXOPENTY)LAMINO)-, CYCLOPENTYL ESTER, (.ALPHA.S)- | Tosedostat [USAN:INN] | (5S, 8S)-8-({(1R)-1-[3, 5-bis
Especificaciones y pureza
≥95%
Mecanismos bioquímicos y fisiológicos
Aminopeptidase inhibitor (IC50values are 100, 150, 220, > 1000, > 5000, > 10000 and > 30000 nM for LAP, PuSA, aminopeptidase N, aminopeptidase B, PILSAP, LTA4hydrolase and MetAP2, respectively). Potently inhibits tumor cell proliferation in a variety of
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Mecanismo de acción
Aminopeptidase inhibitor
Propiedades del producto Nombres e identificadores Pubchem Sid 504767888 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504767888 Sonrisas canónicas CC(C)CC(C(C(=O)NO)O)C(=O)NC(C1=CC=CC=C1)C(=O)OC2CCCC2 IUPAC Name cyclopentyl (2S)-2-[[(2R)-2-[(1S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl]amino]-2-phenylacetate InChIKey FWFGIHPGRQZWIW-SQNIBIBYSA-N INCHI 1S/C21H30N2O6/c1-13(2)12-16(18(24)20(26)23-28)19(25)22-17(14-8-4-3-5-9-14)21(27)29-15-10-6-7-11-15/h3-5,8-9,13,15-18,24,28H,6-7,10-12H2,1-2H3,(H,22,25)(H,23,26)/t16-,17+,18+/m1/s1 Isómeros SMILES CC(C)C[C@H]([C@@H](C(=O)NO)O)C(=O)N[C@@H](C1=CC=CC=C1)C(=O)OC2CCCC2 PubChem CID 15547703 Peso molecular 406.47
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Clase Carboxylic acids and derivatives Subclass Amino acids, peptides, and analogues Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives Direct Parent N-acyl-alpha amino acids and derivatives Alternative Parents Alpha amino acid esters N-acyl amines Monosaccharides Benzene and substituted derivatives Secondary carboxylic acid amides Secondary alcohols Hydroxamic acids Carboxylic acid esters Monocarboxylic acids and derivatives Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aromatic homomonocyclic compounds Substituents Alpha-amino acid ester - N-acyl-alpha amino acid or derivatives - Monocyclic benzene moiety - Fatty amide - Monosaccharide - N-acyl-amine - Benzenoid - Fatty acyl - Secondary alcohol - Hydroxamic acid - Carboxylic acid ester - Secondary carboxylic acid amide - Carboxamide group - Monocarboxylic acid or derivatives - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Alcohol - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Aromatic homomonocyclic compound Descripción This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solvent:DMSO, Max Conc. mg/mL: 40.65, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 20.32, Max Conc. mM: 50 Peso molecular 406.500 g/mol XLogP3 2.300 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 10 Exact Mass 406.21 Da Monoisotopic Mass 406.21 Da Topological Polar Surface Area 125.000 Ų Heavy Atom Count 29 Formal Charge 0 Complexity 555.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 3 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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