Determine the necessary mass, volume, or concentration for preparing a solution.
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≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
trans-Ferulic acid is the naturally occurring isomer of ferulic acid, which finds application as an antioxidant and preservative in food and beverage industry. It is the main phenolic acid found in rye and wheat grain.
A chemopreventive analogue of caffeic acid.trans-4-Hydroxy-3-methoxycinnamic acid is used as an important raw material for the preparation of its corresponding esters by reacting with alcohols.
| Sonrisas canónicas | COC1=C(C=CC(=C1)C=CC(=O)O)O |
|---|---|
| IUPAC Name | (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid |
| InChIKey | KSEBMYQBYZTDHS-HWKANZROSA-N |
| INCHI | 1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+ |
| Isómeros SMILES | COC1=C(C=CC(=C1)/C=C/C(=O)O)O |
| WGK Alemania | 3 |
| RTECS | UD3365500 |
| Peso molecular | 194.18 |
| Beilstein | 1570363 |
| Reaxy-Rn | 1371483 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1371483&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Clase | Cinnamic acids and derivatives |
| Subclass | Hydroxycinnamic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Hydroxycinnamic acids |
| Alternative Parents | Coumaric acids and derivatives Cinnamic acids Methoxyphenols Styrenes Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers 1-hydroxy-2-unsubstituted benzenoids Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Cinnamic acid - Coumaric acid or derivatives - Hydroxycinnamic acid - Methoxyphenol - Phenoxy compound - Anisole - Methoxybenzene - Styrene - Phenol ether - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Phenol - Monocyclic benzene moiety - Benzenoid - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Ether - Organic oxygen compound - Carbonyl group - Organic oxide - Organooxygen compound - Hydrocarbon derivative - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as hydroxycinnamic acids. These are compounds containing an cinnamic acid where the benzene ring is hydroxylated. |
| External Descriptors | Coniferyl alcohol derivatives |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Sep 25, 2025 | F111083 | |
| Certificate of Analysis | Sep 25, 2025 | F111083 | |
| Certificate of Analysis | Sep 25, 2025 | F111083 | |
| Certificate of Analysis | Sep 25, 2025 | F111083 | |
| Certificate of Analysis | Jun 11, 2025 | F111083 | |
| Certificate of Analysis | Jun 11, 2025 | F111083 | |
| Certificate of Analysis | Jun 11, 2025 | F111083 | |
| Certificate of Analysis | Jun 11, 2025 | F111083 | |
| Certificate of Analysis | Apr 03, 2025 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Nov 26, 2022 | F111083 | |
| Certificate of Analysis | Mar 30, 2022 | F111083 | |
| Certificate of Analysis | Jan 27, 2022 | F111083 | |
| Certificate of Analysis | Jan 27, 2022 | F111083 | |
| Certificate of Analysis | Jun 18, 2021 | F111083 | |
| Certificate of Analysis | Jun 18, 2021 | F111083 |
| Solubilidad | Soluble in alcohol and hot water. |
|---|---|
| Sensibilidad | Light & Moisture & Air sensitive. |
| Punto de fusión (°C) | 168-172°C |
| Peso molecular | 194.180 g/mol |
| XLogP3 | 1.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 194.058 Da |
| Monoisotopic Mass | 194.058 Da |
| Topological Polar Surface Area | 66.800 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 224.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
| 1. Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning. (2023) Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol–Feeding Mice. Nutrients, 15 (5): (1078). [PMID:36904078] [10.3390/nu15051078] |
| 2. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2022) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). [PMID:36484340] [10.1039/D2FO02233H] |
| 3. Chunru Wang, Junyao Li, Xiangsheng Han, Shuai Liu, Xintao Gao, Chuanlong Guo, Xiaochen Wu. (2022) Silk sericin stabilized proanthocyanidins for synergetic alleviation of ulcerative colitis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:36007701] [10.1016/j.ijbiomac.2022.08.134] |
| 4. Zhijin Han, Haojie Guo, Yifan Zhou, Liguo Wang, Kun Zhang, Jing-an Li. (2022) Composite Coating Prepared with Ferulic Acid to Improve the Corrosion Resistance and Blood Compatibility of Magnesium Alloy. Metals, 12 (4): (545). [PMID:] [10.3390/met12040545] |
| 5. Wenfei Tian, Jingyang Tong, Xiaoyue Zhu, Philipp Fritschi Martin, Yonghui Li, Zhonghu He, Yan Zhang. (2021) Effects of Different Pilot-Scale Milling Methods on Bioactive Components and End-Use Properties of Whole Wheat Flour. Foods, 10 (11): (2857). [PMID:34829138] [10.3390/foods10112857] |
| 6. Ping Sun, Hui Liu, Mingbao Feng, Xuesheng Zhang, Yingsen Fang, Zhicai Zhai, Virender K. Sharma. (2021) Dual nonradical degradation of acetaminophen by peroxymonosulfate activation with highly reusable and efficient N/S co-doped ordered mesoporous carbon. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2021.118697] |
| 7. Donglai Qi, Qian Li, Chen Chen, Xiang Wang. (2018) Ferulic acid modification enhances the anti-oxidation activity of natural Hb in vitro. Artificial Cells Nanomedicine and Biotechnology, [PMID:29533098] [10.1080/21691401.2018.1448987] |
| 8. Zicong Zeng, Yuting Li, Rong Yang, Chengmei Liu, Xiuting Hu, Shunjing Luo, Ersheng Gong, Jiangping Ye. (2017) The relationship between reducing sugars and phenolic retention of brown rice after enzymatic extrusion. JOURNAL OF CEREAL SCIENCE, [PMID:] [10.1016/j.jcs.2017.02.016] |
| 9. Jingwen Xiao, Shilin Zhou, Fengshu Fei, Lin Long, Chuanlong Guo. (2025) Pectin-loaded ferulic acid nanoparticles: A potential therapeutic strategy for ulcerative colitis via modulation of the cGAS-STING pathway. TOXICOLOGY AND APPLIED PHARMACOLOGY, [PMID:40174805] [10.1016/j.taap.2025.117317] |
| 10. Kunying Nie, Jiali Zhang, Haitao Xu, Keyun Ren, Chunlei Yu, Qi Zhang, Falan Li, Qingqing Yang. (2024) Reverse design of haptens based on antigen spatial conformation to prepare anti-capsaicinoids&gingerols antibodies for monitoring of gutter cooking oil. Food Chemistry-X, [PMID:38524780] [10.1016/j.fochx.2024.101273] |
| 11. Yuandong Yu, Guizhao Liang. (2021) Interaction mechanism of phenolic acids and zein: A spectrofluorometric and molecular dynamics investigation. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2021.118032] |
| 12. Stoyan Dirimanov, Petra Högger. (2019) Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features. Biomolecules, 9 (6): (219). [PMID:31195734] [10.3390/biom9060219] |
| 13. Dan Liu, Yaokun Pang, Shenrui Pan, Jianxia Sun. (2025) Antimicrobial activity and mechanism of ferulic acid in combination with UV-A light against Escherichia coli and its application on chicken preservation. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, [PMID:40334545] [10.1016/j.ijfoodmicro.2025.111234] |