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GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
Synonyms
Depthon | Ricifon | Tugon | Foschlor R-50 | Ciclosom | Dyrex | Votexit | Briten | Metrifonate | NCI-C54831 | Flibol E | HSDB 881 | Khloroftalm | Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester | Briton | Danex | Metriphonatum | Bayer-L-
Storage
Store at 2-8°C
Shipped In
Wet ice,FedEx DG Service
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
50mg
T108160-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
69,90US$
250mg
T108160-250mg
5
279,90US$
Enter a quantity for the sizes you want to add.

Descripción general

It has a pleasant odor. It's relatively stable in neutral and weak solutions, but its solution will deteriorate over time. In alkaline solutions, it converts into dichlorvos, and this conversion process accelerates with increased alkalinity and temperature. It decomposes when heated to 180°C. Its solubility in water at 20°C is 15.4g/100ml. It's soluble in benzene, ethanol, and most chlorinated hydrocarbons, slightly soluble in ether and carbon tetrachloride, and insoluble in glycerol. It's moderately toxic, with an oral lethal dose for male rats of 630mg/kg. It's corrosive to metals.

Specifications

Sinónimos
Depthon | Ricifon | Tugon | Foschlor R-50 | Ciclosom | Dyrex | Votexit | Briten | Metrifonate | NCI-C54831 | Flibol E | HSDB 881 | Khloroftalm | Phosphonic acid, (2, 2, 2-trichloro-1-hydroxyethyl)-, dimethyl ester | Briton | Danex | Metriphonatum | Bayer-L-
Especificaciones y pureza
analytical standard, Moligand™, ≥99%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C
Enviado en
Wet ice, FedEx DG Service
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Analytical standard, Moligand™
Tipo de acción
INHIBITOR
Pureza
≥99%
Propiedades del producto
ALogP0.5
Nombres e identificadores
Sonrisas canónicasCOP(=O)(C(C(Cl)(Cl)Cl)O)OC
IUPAC Name2,2,2-trichloro-1-dimethoxyphosphorylethanol
InChIKeyNFACJZMKEDPNKN-UHFFFAOYSA-N
INCHI1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3
Isómeros SMILES COP(=O)(C(C(Cl)(Cl)Cl)O)OC
WGK Alemania 3
RTECS TA0700000
PubChem CID 5853
Número ONU 2783(solid)3018(liquid)
Grupo de embalaje I
Peso molecular 257.44
Beilstein 1709434

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClaseOrganic phosphonic acids and derivatives
SubclassPhosphonic acid diesters
Intermediate Tree Nodes Not available
Direct ParentDialkyl alkylphosphonates
Alternative Parents Phosphonic acid esters  Chlorohydrins  Organopnictogen compounds  Organophosphorus compounds  Organooxygen compounds  Organochlorides  Organic oxides  Hydrocarbon derivatives  Alkyl chlorides  
Molecular FrameworkAliphatic acyclic compounds
Substituents Dialkyl alkylphosphonate - Phosphonic acid ester - Halohydrin - Chlorohydrin - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organophosphorus compound - Organooxygen compound - Organochloride - Organohalogen compound - Alkyl halide - Alkyl chloride - Aliphatic acyclic compound
DescripciónThis compound belongs to the class of organic compounds known as dialkyl alkylphosphonates. These are compounds containing a phosphonic acid that is diesterified with alkyl groups, and the phosphorus atom is also directly attached to an alkyl group.
External Descriptors Organophosphorus insecticides
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Diabrotica undecimpunctata (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lucilia cuprina (24 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cheumatopsyche (45 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Anomala orientalis (27 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bactrocera dorsalis (116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Popillia japonica (46 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Amphimallon majale (27 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Daphnia magna (43 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Maladera castanea (27 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

14 results found

Lot NumberCertificate TypeFechaArticulo
D2622484Certificate of AnalysisMar 20, 2026 T108160
D2622489Certificate of AnalysisMar 20, 2026 T108160
B2626170Certificate of AnalysisMay 23, 2025 T108160
F2510719Certificate of AnalysisMay 23, 2025 T108160
F2510720Certificate of AnalysisMay 23, 2025 T108160
K2503023Certificate of AnalysisMay 23, 2025 T108160
B2313593Certificate of AnalysisNov 04, 2024 T108160
D2530362Certificate of AnalysisJun 26, 2024 T108160
B2507049Certificate of AnalysisApr 10, 2024 T108160
F2421373Certificate of AnalysisApr 10, 2024 T108160
F2421374Certificate of AnalysisApr 10, 2024 T108160
F2421391Certificate of AnalysisApr 10, 2024 T108160
G2215461Certificate of AnalysisApr 07, 2024 T108160
G2130245Certificate of AnalysisMay 09, 2023 T108160

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Propiedades químicas y físicas
Índice de refracción1.3439
Punto de fusión (°C)83-84°C
Peso molecular257.430 g/mol
XLogP30.500
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass255.923 Da
Monoisotopic Mass255.923 Da
Topological Polar Surface Area55.800 Ų
Heavy Atom Count12
Formal Charge0
Complexity183.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Referencias
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2. Liu Shuai, Zhao Jingkai, Wu Junfeng, Wang Ling, Hu Jiandong, Li Shixin, Zhang Hao.  (2023)  A deep learning-enabled smartphone platform for rapid and sensitive colorimetric detection of dimethoate pesticide.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (29): (7127-7138).  [PMID:37770666] [10.1007/s00216-023-04978-z]
3. Shaofeng Yuan, Hang Yu, Yahui Guo, Yunfei Xie, Yuliang Cheng, He Qian, Weirong Yao.  (2023)  Removal of trichlorfon and phoxim from pak choi (Brassica campestris ssp. chinensis) by combined ultrasonic and ozone treatment and their effects on quality.  JOURNAL OF FOOD PROCESS ENGINEERING,  46  (12): (e14458).  [PMID:] [10.1111/jfpe.14458]
4. Shuhua Li, Jizhong Wu, Shen Zhang, Tianhui Jiao, Jie Wei, Xiaomei Chen, Qingmin Chen, Quansheng Chen.  (2023)  Inner filter effect-based upconversion nanosensor for rapid detection of thiram pesticides using upconversion nanoparticles and dithizone–cadmium complexes.  FOOD CHEMISTRY,      [PMID:37713750] [10.1016/j.foodchem.2023.137438]
5. Ruizhi Li, Wenrui Zhang, Fanxing Meng, Xinbo Li, Zongda Li, Yan Fang, Minwei Zhang.  (2023)  Hollow Prussian blue with ultrafine silver nanoparticle agents (Ag-HPB) integrated sensitive and flexible biosensing platform with highly enzyme loading capability.  TALANTA,      [PMID:37556951] [10.1016/j.talanta.2023.125036]
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7. Lingling Qin, Yujie Guo, Lingfei Li, Dan Lin, Yucheng Li, Shihao Xu, Changlong Jiang.  (2023)  Ratiometric Fluorescent Sensor Based on Hydrogen-Bond Triggering the Internal Filter Effect for Enzyme-Free and Visual Monitoring Pesticide Residues.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.3c00772]
8. Kai Zhang, Liangzi Wang, Jingitao liu, Shiyu Zhao, Longfei Ding, Binhua Zhou, Bo Zhao.  (2023)  A Highly Sensitive Electrochemical Methamidophos Immobilized AChE Biosensor for Organophosphorus Pesticides Detection.  International Journal of Electrochemical Science,      [PMID:] [10.20964/2022.04.44]
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10. Yizhong Shen, Xiang Gao, Huanhuan Chen, Yunlong Wei, Hui Yang, Ying Gu.  (2023)  Ultrathin C3N4 nanosheets-based oxidase-like 2D fluorescence nanozyme for dual-mode detection of organophosphorus pesticides.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:36913745] [10.1016/j.jhazmat.2023.131171]
11. Wanqi Jiang, Zan Yang, Fei Tong, Siyu Zhang, Lu Zhu, Lei Wang, Lunjing Huang, Kang Liu, Mingming Zheng, Yibin Zhou, Ruyan Hou, Yingnan Liu.  (2023)  Two birds with one stone: An enzyme-regulated ratiometric fluorescent and photothermal dual-mode probe for organophosphorus pesticide detection.  BIOSENSORS & BIOELECTRONICS,      [PMID:36638562] [10.1016/j.bios.2023.115074]
12. Yixuan Xia, Zhigang Xiao, Yinhui Yi, Tingting Liu, Conglin Zhang, Gangbing Zhu.  (2022)  Nitrogen-doped hollow bowl-like carbon as highly effective sensing material for electroanalysis.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2022.108094]
13. Biao Zhang, Ruofan Zhou, Huiqi Zhang, Danfeng Cai, Xiaodong Lin, Yihan Lang, Yulou Qiu, Xuping Shentu, Zihong Ye, Xiaoping Yu.  (2022)  A Smartphone Colorimetric Sensor Based on Pt@Au Nanozyme for Visual and Quantitative Detection of Omethoate.  Foods,  11  (18): (2900).  [PMID:36141028] [10.3390/foods11182900]
14. Xueli Luo, Gengli Huang, Yuchen Li, Jie Guo, Xiaokai Chen, Youwen Tan, Wenzhi Tang, Zhonghong Li.  (2022)  Dual-modes of ratiometric fluorescent and smartphone-integrated colorimetric detection of glyphosate by carbon dots encapsulated porphyrin metal–organic frameworks.  APPLIED SURFACE SCIENCE,      [PMID:] [10.1016/j.apsusc.2022.154368]
15. Ruoxuan Jiang, Dan Lin, Qianru Zhang, Lingfei Li, Liang Yang.  (2021)  Multiplex chroma-response based fluorescent smartphone sensing platform for rapid and visual quantitative determination of antibiotic residues.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2021.130902]
16. Shaofeng Yuan, Changjian Li, Hang Yu, Yunfei Xie, Yahui Guo, Weirong Yao.  (2021)  Selective uptake determines the variation in degradation of organophosphorus pesticides by Lactobacillus plantarum.  FOOD CHEMISTRY,      [PMID:34034058] [10.1016/j.foodchem.2021.130106]
17. Shaofeng Yuan, Changjian Li, Hang Yu, Yunfei Xie, Yahui Guo, Weirong Yao.  (2021)  Screening of lactic acid bacteria for degrading organophosphorus pesticides and their potential protective effects against pesticide toxicity.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2021.111672]
18. Kun Feng, Meng-Yu Zhai, Yun-Shan Wei, Min-Hua Zong, Hong Wu, Shuang-Yan Han.  (2021)  Fabrication of Nano/Micro-Structured Electrospun Detection Card for the Detection of Pesticide Residues.  Foods,  10  (4): (889).  [PMID:33921560] [10.3390/foods10040889]
19. Guozheng Zhao, Binhua Zhou, Xiuwen Wang, Jian Shen, Bo Zhao.  (2021)  Detection of organophosphorus pesticides by nanogold/mercaptomethamidophos multi-residue electrochemical biosensor.  FOOD CHEMISTRY,      [PMID:33735695] [10.1016/j.foodchem.2021.129511]
20. Xiaomin Xie, Binhua Zhou, Yonglei Zhang, Guozheng Zhao, Bo Zhao.  (2021)  A multi-residue electrochemical biosensor based on graphene/chitosan/parathion for sensitive organophosphorus pesticides detection.  CHEMICAL PHYSICS LETTERS,      [PMID:] [10.1016/j.cplett.2021.138355]
21. Jianhui Zhen, Gang Liang, Ruichun Chen, Wenshen Jia.  (2020)  Label-free hairpin-like aptamer and EIS-based practical, biostable sensor for acetamiprid detection.  PLoS One,  15  (12): (e0244297).  [PMID:33362222] [10.1371/journal.pone.0244297]
22. Linfeng Chen, Xike Tian, Yong Li, Liqiang Lu, Yulun Nie, Yanxin Wang.  (2020)  Broad-spectrum pesticide screening by multiple cholinesterases and thiocholine sensors assembled high-throughput optical array system.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:33254811] [10.1016/j.jhazmat.2020.123830]
23. Zhifeng Cai, Shulin Pang, Xinru Ma, Li Zhu, Yefan Zhang, Fang Tian, Caifeng Zhang.  (2020)  One-pot green and simple synthesis of polyvinyl pyrrolidone capped for copper nanoclusters for high selectivity sensing of fluazinam.  Micro & Nano Letters,  15  (9): (606-609).  [PMID:] [10.1049/mnl.2019.0757]
24. Liu Yaqing, Lin Xiaodong, Ji Xiangyi, Hao Zhe, Tao Zhanhui.  (2020)  Smartphone-based enzyme-free fluorescence sensing of organophosphate DDVP.  MICROCHIMICA ACTA,  187  (7): (1-8).  [PMID:32613298] [10.1007/s00604-020-04384-7]
25. Yujie Zhang, Yunlong Huang, Ling Fu, Jiaoyan Qiu, Zhuqing Wang, Aiguo Wu.  (2020)  Colorimetric detection of paraquat in aqueous and fruit juice samples based on functionalized gold nanoparticles.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2020.103574]
26. Shuhuai Li, Chaohai Pang, Xionghui Ma, Haibo Li, Min Zhao, Chunhua Liu, Jinhui Luo.  (2020)  A gold nanoparticle-loaded molecularly imprinted switch sensor with high sensitivity to ethephon.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2020.105025]
27. Yu Qianru, He Chuxian, Li Qian, Zhou You, Duan Nuo, Wu Shijia.  (2020)  Fluorometric determination of acetamiprid using molecularly imprinted upconversion nanoparticles.  MICROCHIMICA ACTA,  187  (4): (1-10).  [PMID:32166414] [10.1007/s00604-020-4204-0]
28. Fenglian Qi, Yunhe Lan, Zihui Meng, Chunxiao Yan, Shuguang Li, Min Xue, Yifei Wang, Lili Qiu, Xuan He, Xueyong Liu.  (2018)  Acetylcholinesterase-functionalized two-dimensional photonic crystals for the detection of organophosphates.  RSC Advances,  (51): (29385-29391).  [PMID:35548014] [10.1039/C8RA04953J]
29. Kaiqiang Wang, Da-Wen Sun, Hongbin Pu, Qingyi Wei.  (2018)  Surface-enhanced Raman scattering of core-shell Au@Ag nanoparticles aggregates for rapid detection of difenoconazole in grapes.  TALANTA,      [PMID:30262083] [10.1016/j.talanta.2018.08.005]
30. Liu Qingju, Han Ping, Gong Wenwen, Wang Hui, Feng Xiaoyuan.  (2018)  Colorimetric determination of the pesticide chlorothalonil based on the aggregation of gold nanoparticles.  MICROCHIMICA ACTA,  185  (7): (1-7).  [PMID:29971610] [10.1007/s00604-018-2890-7]
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33. Xiaoxia Kang, Jige Yuan, Xijuan Gu, Xiaoyan Li, Tao Wen, Miao He, Yue He, Xiaoxiao Yang, Yuechen Li, Conglin Guo, Haiwei Ji, Yuling Qin, Li Wu.  (2025)  DNA-Templated Ag Nanocluster/CdSe@ZnS Quantum Dot-Based Platform for Colorimetric and Fluorescence Detection of Organophosphorus Pesticide.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.4c06928]
34. Xin Liu, Shiyue Niu, Bin Yang, Jia Liu, Liqian Niu, Xian Wang, Daqian Song, Shuyun Bi.  (2025)  Fabrication of BSA-protected AgNPs modified MIL-53(Al) as SERS substrate for trace determination of diquat and dipterex.  TALANTA,      [PMID:40154046] [10.1016/j.talanta.2025.128002]
35. Ziyi Qin, Jinju Xu, Yuanxin Cao, Chunhui Liao, Tian Lan, Shuyun Shi.  (2025)  Visual detection of glyphosate by Al3+-regulated carbon dots/CdTe quantum dots ratiometric fluorescent sensing platform.  FOOD CHEMISTRY,      [PMID:39893924] [10.1016/j.foodchem.2025.143070]
36. Junjie Qi, Wenhui Hao, Jingkun Li, Yuqi Wan, Guoyong Jiang, Yukihiro Ozaki, Fuwei Pi.  (2025)  PCN222(Fe)@NU-1000 based MOF-on-MOF dual-signal sensing strategy for sensitive detection of phoxim.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.115260]
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