10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.
In vitro
Tylosin tartrate (25 mg/L) significantly inhibits methane production relative to unamended controls, thus indicating that Tylosin tartrate at concentrations commonly found in swine lagoons can negatively impact anaerobic metabolism. Tylosin disappearance follows a biphasic pattern, where rapid initial loss is followed by a slow removal phase. The 90% disappearance times for tylosin, relomycin (tylosin D), and desmycosin (tylosin B) in anaerobically incubated slurries are 30 to 130 hours, and aerating the slurries reduced the 90% disappearance times to between 12 and 26 hours. Tylosin tartrate is stable for at least one month when stored in Milli-Q water at pH 5.7 to 6.7 at 22 ℃.
In vivo
Tylosin increases splenocyte proliferation and splenocyte conditioned medium (CM) proliferative activity above control levels from whole splenocyte cultures in chickens. Tylosin also increases antitumor activity of splenocytes in chickens. Tylosin tartrate (50 mg/kg) administered orally twice daily for 10 days, beginning 14 days after intranasal infection, significantly reduces the incidence and severity of macroscopical pneumonic lung lesions in neonatal piglets. After tylosin tartrate administered intravenously (i.v.) at 10 mg/kg in camels, serum tylosin concentrations in the water-deprived camels are significantly higher, rate of drug elimination is slower, the volume of distribution is significantly smaller, and total body clearance is significantly slower than in the normal camels. On the other hand, serum tylosin concentrations are lower in the water deprived camels and the mean absorption time is significantly shorter in camels treat with tylosin tartrate (20 mg/kg i.m.).
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥96%
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Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| 1. Liubing Fan, Shiqiang Hao, Shihui He, Xusheng Zhang, Mingyang Li, Christopher Wolverton, Jing Zhao, Quanlin Liu. (2023) Luminescent hybrid halides with various centering metal cations (Zn, Cd and Pb) and diverse structures. DALTON TRANSACTIONS, 52 (16): (5119-5126). [PMID:36961101] [10.1039/D2DT04067K] |
| 2. Bing Wang, Qingtong Cao, Ming Cheng, Guomin Li, Jian Zhang, Hong Jiang. (2023) Photocatalytic degradation of antibiotics in water by pollution-free photocatalytic films with a three-dimensional layered structure and the reaction mechanism study. Journal of Water Process Engineering, [PMID:] [10.1016/j.jwpe.2023.103550] |
| 3. Tian-Yu Qiu, Ying-Nan Zhao, Wen-Si Tang, Hua-Qiao Tan, Hui-Ying Sun, Zhen-Hui Kang, Xia Zhao, Yang-Guang Li. (2022) Smart Covalent Organic Framework with Proton-Initiated Switchable Photocatalytic Aerobic Oxidation. ACS Catalysis, [PMID:] [10.1021/acscatal.2c03796] |
| 4. Wang-Xi Fan, Zefang Li, Zhou Yang, Jun-Fei Ou, Meng Xiang, Zhong-Li Qin. (2022) Improving the curing and flame retardancy of epoxy resin composites by multifunctional Si-containing cyclophosphazene derivatives. RSC Advances, 12 (22): (13756-13764). [PMID:35530380] [10.1039/D1RA08843B] |
| 5. Xin Chen, Duanxiu Li, Yanwen Duan, Yong Huang. (2022) Characterization of co-amorphous sinomenine-tranilast systems with strong intermolecular interactions and sustained release profiles. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.jddst.2022.103296] |
| 6. Haiyun Li, Yizhi Qiu, Tuo Yao, Yachun Ma, Huirong Zhang, Xiaolei Yang, Changning Li. (2019) Evaluation of seven chemical pesticides by mixed microbial culture (PCS-1): Degradation ability, microbial community, and Medicago sativa phytotoxicity. JOURNAL OF HAZARDOUS MATERIALS, [PMID:31843407] [10.1016/j.jhazmat.2019.121834] |
| 7. Zhiyan Huang, Tenglu Wang, Minxian Shen, Zhujian Huang, Yunxiao Chong, Lihua Cui. (2019) Coagulation treatment of swine wastewater by the method of in-situ forming layered double hydroxides and sludge recycling for preparation of biochar composite catalyst. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2019.03.136] |
| 8. Chan-Yuan YAO, Jin-Yi YANG, Zhen-Lin XU, Hong WANG, Hong-Tao LEI, Yuan-Ming SUN, Yuan-Xin TIAN, Yu-Dong SHEN. (2018) Indirect Competitive Enzyme-Linked Immunosorbent Assay for Detection of Tylosin in Milk and Water Samples. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, [PMID:] [10.1016/S1872-2040(18)61106-5] |
| 9. Tianlu Xu, Chunling Zhang, Peihong Li, Xueyan Dai, Lijie Qu, Yanlong Sui, Jinjia Gu, Yanli Dou. (2018) Preparation of dual-functionalized graphene oxide for the improvement of the thermal stability and flame-retardant properties of polysiloxane foam. NEW JOURNAL OF CHEMISTRY, 42 (16): (13873-13883). [PMID:] [10.1039/C8NJ02361A] |
| 10. Dong Zhou, Ruliang Liu, Yan-Bing He, Fengyun Li, Ming Liu, Baohua Li, Quan-Hong Yang, Qiang Cai, Feiyu Kang. (2016) SiO2 Hollow Nanosphere-Based Composite Solid Electrolyte for Lithium Metal Batteries to Suppress Lithium Dendrite Growth and Enhance Cycle Life. Advanced Energy Materials, 6 (7): (1502214). [PMID:] [10.1002/aenm.201502214] |
| 11. Yuehong Song, Shanshan Song, Liqiang Liu, Hua Kuang, Lingling Guo, Chuanlai Xu. (2015) Simultaneous detection of tylosin and tilmicosin in honey using a novel immunoassay and immunochromatographic strip based on an innovative hapten. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:] [10.1080/09540105.2015.1089843] |
| 12. Yuzhen Xu, Liyan Qiu. (2015) Nonspecifically enhanced therapeutic effects of vincristine on multidrug-resistant cancers when coencapsulated with quinine in liposomes. International Journal of Nanomedicine, [PMID:26170660] [10.2147/IJN.S84555] |
| 13. Yvhao Xie, Xinxin Li, Qingshi Meng, Jinjun Li, Xin Wang, Liying Zhu, Weiwei Wang, Xiaoqiong Li. (2024) Interplay between gut microbiota and tryptophan metabolism in type 2 diabetic mice treated with metformin. Microbiology Spectrum, [PMID:39162538] [10.1128/spectrum.00291-24] |
| 14. Xiangqian Li, Jiapei Gu, Zhan Zhou, Wanqiang Liu, Jinwei Gao, Qianming Wang. (2019) Precise control for the aggregation and deaggregation with the aid of a tetraphenylethylene derivative: Luminescence modulation and sensing performance. DYES AND PIGMENTS, [PMID:] [10.1016/j.dyepig.2019.107844] |
