Uricase from Candida utilis, CAS No.9002-12-4

CAS: 9002-12-4 Cat. No.: U128546 Número EC: 232-655-5 PubChem CID: 14228836
Disponible para pedir
GRADE & PURITY EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. ≥2 units/mg dry weight
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Size
Estado
Price
Qty
100U
U128546-100UN
1
617,90US$
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Why this grade

EnzymoPure™, ≥2 units/mg dry weight EnzymoPure™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid. Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.
Oxidizes uric acid

Specifications

Product Name
Uricase from Candida utilis, CAS No.9002-12-4
Sinónimos
FT-0772402 | Uricase from Bacillus fastidiosus, lyophilized, ~9 U/mg | Uricase from Candida sp., recombinant, expressed in E. coli, lyophilized powder, >=2 units/mg solid | VPXDHZMLJOJKOX-UHFFFAOYSA-N | Uricase from Arthrobacter globiformis, lyophilized p
Grado
EnzymoPure™
Especificaciones y pureza
EnzymoPure™, ≥2 units/mg dry weight
Mecanismos bioquímicos y fisiológicos
Suitable for the determination of uric acid in clinical analysis.
CAS
9002-12-4
Número de la Comisión de Enzimas
1.7.3.3
Tipo de molécula
Enzyme
Almacenamiento y envío
Concentración
≥2 units/mg dry weight
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Definición de unidad
One Unit oxidizes one micromole of uric acid per minute

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeFechaArticulo
D2502559Certificate of AnalysisMar 18, 2025 U128546
D2429469Certificate of AnalysisMar 14, 2024 U128546
D2429470Certificate of AnalysisMar 14, 2024 U128546
I2305219Certificate of AnalysisAug 15, 2023 U128546
D2230082Certificate of AnalysisMar 03, 2022 U128546
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Zheng Xinyu, Yang Yang, Gao Feng, Li Huihui, Yang Weikang, Guo Dong-Yu, Chen Shengming, Pan Qinhe.  (2022)  Enzyme-free fluorescence determination of uric acid by combining CdTe quantum dots with metal–organic framework for signal amplification.  MICROCHIMICA ACTA,  189  (11): (1-9).  [PMID:36318325] [10.1007/s00604-022-05535-8]
2. Fuad Abduro Bushira, Shimeles Addisu Kitte, Yong Wang, Haijuan Li, Ping Wang, Yongdong Jin.  (2021)  Plasmon-Boosted Cu-Doped TiO2 Oxygen Vacancy-Rich Luminol Electrochemiluminescence for Highly Sensitive Detection of Alkaline Phosphatase.  ANALYTICAL CHEMISTRY,      [PMID:34743510] [10.1021/acs.analchem.1c03842]
3. Guojun Cao, Can Wu, Yong Tang, Chidan Wan.  (2019)  Ultrasmall HKUST-1 nanoparticles decorated graphite nanosheets for highly sensitive electrochemical sensing of DNA damage biomarker 8-hydroxy-2’-deoxyguanosine.  ANALYTICA CHIMICA ACTA,      [PMID:30851856] [10.1016/j.aca.2019.01.031]
4. Aijin Fang, Qiongqiong Wu, Qiujun Lu, Hongyu Chen, Haitao Li, Meiling Liu, Youyu Zhang, Shouzhuo Yao.  (2016)  Upconversion ratiometric fluorescence and colorimetric dual-readout assay for uric acid.  BIOSENSORS & BIOELECTRONICS,      [PMID:27471157] [10.1016/j.bios.2016.07.055]
5. Yuanting Xie, Kaidi Li, Jing Liu, Ying Zhou, Chuangjie Zhang, Yan Yu, Jianlong Wang, Lei Su, Xueji Zhang.  (2024)  A smart lab on a wearable microneedle patch with convolutional neural network-enhanced colorimetry for early warning of syndrome of inappropriate antidiuretic hormone secretion.  Aggregate,      [PMID:] [10.1002/agt2.671]
6. Zehua Guo, Yiren Cao, Liuyin Fan, Weiwen Liu, Li Wei, Yixin Ma, Jicun Ren, Qiang Zhang, Chengxi Cao.  (2024)  A temperature-independent model of dual calibration standards for onsite and point-of-care quantification analyses via electrophoresis titration chip.  ANALYTICA CHIMICA ACTA,      [PMID:38245206] [10.1016/j.aca.2024.342207]
7. Yanshu Xiang, Yongjie Zhao, Yifan Jiang, Jiarui Feng, Xiaoyi Zhang, Wei Su, Yingjie Zhou, Peng Wei, Sze Shin Low, Hao Nan Li.  (2024)  Battery-Free and Multifunctional Microfluidic Janus Wound Dressing with Biofluid Management, Multi-Indicator Monitoring, and Antibacterial Properties.  ACS Applied Materials & Interfaces,      [PMID:39264683] [10.1021/acsami.4c09891]
8. Yunfeng Bai, Xiaoxuan Fan, Guoning Chen, Zhilong Zhao.  (2024)  Efficient and fast detection of uric acid based on a colorimetric sensing method.  Analytical Methods,      [PMID:39157953] [10.1039/D4AY01053A]
9. Yi-Kun Wang, Ya-Jun Chen, Yao Pan, Yu Hai-Yin.  (2024)  Prussian Blue and Polyvinylpyrrolidone-Embedded Hollow Fiber Gradient Polysulfone Membrane for Uric Acid Biosensor Application.  JOURNAL OF APPLIED POLYMER SCIENCE,      [PMID:] [10.1002/app.56649]
10. Chenlong He, Huawei Liu, Ming Yin, Jing Chen, Wensi Huang, Han Zhou, Shengming Wu, Yilong Wang.  (2025)  UOx@HMnO2 Biozyme-Nanozyme Driven Electrochemical Platform for Specific Uric Acid Bioassays.  ANALYST,      [PMID:40035522] [10.1039/D4AN01512F]
11. Ziting Bao, Sheng Lu, Duo Zhang, Guanyu Wang, Xiaolin Cui, Guozhen Liu.  (2024)  Wearable Microneedle Patch for Colorimetric Detection of Multiple Signature Biomarkers in vivo Toward Diabetic Diagnosis.  Advanced Healthcare Materials,      [PMID:38353398] [10.1002/adhm.202303511]
12. Fangbing Wang, Jing Ren, Qiwen Peng, Hongyi Sun, Qiankun Zeng, Yongheng Zhang, Guoyue Shi, Min Zhang.  (2024)  Janus Separation-Sensing Membrane Hosted with Enzyme@MOF Nanoreactor for Real-Time Blood Sensing.  ANALYTICAL CHEMISTRY,      [PMID:39264829] [10.1021/acs.analchem.4c03285]
13. Chunjiao Qi, Jintao Chen, Yuhui Shang, Yu Yang, Kangyan Wang, Jinyang Chen.  (2024)  Target-Triggered Ultrafast Chondroitin Gelation Enabled Power-Free and Point-of-Care Bioassays.  ANALYTICAL CHEMISTRY,      [PMID:39436985] [10.1021/acs.analchem.4c04130]
14. Xiwang Hou, Tianhao Chen, Chunyan Wang, Fanyu Liu, Minggang Zhao, Ye Ma.  (2025)  Analyte mediated transformation of metasurface: A dual-mode plasmonic sensing platform for uric acid.  TALANTA,      [PMID:41166825] [10.1016/j.talanta.2025.129024]
15. Ruoxuan Jiang, Lei Pan, Fan Yang, Shudong Zhang, Dan Lin, Changlong Jiang.  (2025)  MOF-on-MOF multi-enzyme cascade sensor for visual monitoring of uric acid in body fluids.  TALANTA,      [PMID:41240652] [10.1016/j.talanta.2025.129115]
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