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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items VER-155008 - ≥98%(HPLC) , CAS No.1134156-31-2
Synonyms
4-({[(2R,3S,4R,5R)-5-(6-amino-8-{[(3,4-dichlorophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}methyl)benzonitrile | SMR004701641 | HMS1920N16 | AC-33008 | 1134156-31-2 | A848921 | DTXSID00649014 | 4io8 | 5'-O-[(4-Cyanophenyl)methyl]-
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
4-({[(2R, 3S, 4R, 5R)-5-(6-amino-8-{[(3, 4-dichlorophenyl)methyl]amino}-9H-purin-9-yl)-3, 4-dihydroxyoxolan-2-yl]methoxy}methyl)benzonitrile | SMR004701641 | HMS1920N16 | AC-33008 | 1134156-31-2 | A848921 | DTXSID00649014 | 4io8 | 5'-O-[(4-Cyanophenyl)methyl]-
Especificaciones y pureza
≥98%(HPLC)
Mecanismos bioquímicos y fisiológicos
Novel adenosine-derived inhibitor of Heat Shock Protein 70 (Hsp70) (IC50= 0.5μM). Inhibits cell proliferation of multiple human tumor cell linesin vitro. Also binds Hsc70 and Grp78; displays selectivity against Hsp90β(IC50>200μM for Hsp90β).
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nombres e identificadores Sonrisas canónicas C1=CC(=CC=C1COCC2C(C(C(O2)N3C4=NC=NC(=C4N=C3NCC5=CC(=C(C=C5)Cl)Cl)N)O)O)C#N IUPAC Name 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile InChIKey ZXGGCBQORXDVTE-UMCMBGNQSA-N INCHI 1S/C25H23Cl2N7O4/c26-16-6-5-15(7-17(16)27)9-30-25-33-19-22(29)31-12-32-23(19)34(25)24-21(36)20(35)18(38-24)11-37-10-14-3-1-13(8-28)2-4-14/h1-7,12,18,20-21,24,35-36H,9-11H2,(H,30,33)(H2,29,31,32)/t18-,20-,21-,24-/m1/s1 Isómeros SMILES C1=CC(=CC=C1COC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=NC=NC(=C4N=C3NCC5=CC(=C(C=C5)Cl)Cl)N)O)O)C#N WGK Alemania 3 PubChem CID 25195348 Peso molecular 556.4
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Nucleosides, nucleotides, and analogues Clase Purine nucleosides Subclass Not available Intermediate Tree Nodes Not available Direct Parent Purine nucleosides Alternative Parents Glycosylamines 6-aminopurines Pentoses Benzylethers Benzonitriles Benzylamines Dichlorobenzenes Secondary alkylarylamines Aminopyrimidines and derivatives Aminoimidazoles Aryl chlorides N-substituted imidazoles Imidolactams Tetrahydrofurans Heteroaromatic compounds Secondary alcohols 1,2-diols Dialkyl ethers Nitriles Azacyclic compounds Oxacyclic compounds Organochlorides Organopnictogen compounds Primary amines Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Purine nucleoside - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Pentose monosaccharide - Benzylether - Imidazopyrimidine - Purine - Benzonitrile - Benzylamine - 1,2-dichlorobenzene - Aminopyrimidine - Chlorobenzene - Halobenzene - Secondary aliphatic/aromatic amine - Benzenoid - Imidolactam - Pyrimidine - Aminoimidazole - Aryl chloride - Aryl halide - N-substituted imidazole - Monosaccharide - Monocyclic benzene moiety - Tetrahydrofuran - Azole - Imidazole - Heteroaromatic compound - Secondary alcohol - 1,2-diol - Secondary amine - Nitrile - Carbonitrile - Organoheterocyclic compound - Dialkyl ether - Ether - Oxacycle - Azacycle - Organic oxygen compound - Organooxygen compound - Primary amine - Amine - Organopnictogen compound - Hydrocarbon derivative - Organic nitrogen compound - Organonitrogen compound - Alcohol - Organochloride - Organohalogen compound - Aromatic heteropolycyclic compound Descripción This compound belongs to the class of organic compounds known as purine nucleosides. These are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solvent:DMSO, Max Conc. mg/mL: 55.64, Max Conc. mM: 100 Peso molecular 556.400 g/mol XLogP3 2.400 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 10 Rotatable Bond Count 8 Exact Mass 555.119 Da Monoisotopic Mass 555.119 Da Topological Polar Surface Area 164.000 Ų Heavy Atom Count 38 Formal Charge 0 Complexity 831.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 4 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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