Veratridine - Moligand™, ≥97% , Activator of Na v1.1;Activator of Na v1.2;Activator of Na v1.3;Activator of Na v1.4;Activator of Na v1.5;Activator of Na v1.6;Activator of Na v1.7;Activator of Na v1.8, CAS No.71-62-5, Activator of Na v1.1;Activator of Na v1.2;Activator of Na v1.3;Activator of Na v1.4;Activator of Na v1.5;Activator of Na v1.6;Activator of Na v1.7;Activator of Na v1.8

Name: Veratridine - Moligand™, ≥97% , Activator of Na v1.1;Activator of Na v1.2;Activator of Na v1.3;Activator of Na v1.4;Activator of Na v1.5;Activator of Na v1.6;Activator of Na v1.7;Activator of Na v1.8, CAS No.71-62-5, Activator of Na v1.1;Activator of Na v1.2;Activator of Na v1.3;Activator of Na v1.4;Activator of Na v1.5;Activator of Na v1.6;Activator of Na v1.7;Activator of Na v1.8
Brand: Aladdin Scientific
SKU: V275475
Availability: InStock

CAS: 71-62-5 Cat. No.: V275475 Fórmula: C₃₆H₅₁NO₁₁ Peso molecular: 673.8 Número EC: 200-758-4 PubChem CID: 6280

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Veratridine - Moligand™, ≥97% CAS No(71-62-5) V275475 by Aladdin Scientific

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Disponible para pedir

CALIDAD & PUREZA Moligand™ ? ≥97%

Synonyms

HMS3402L17 | [(1R,2S,6S,9S,10R,11S,12S,14R,15S,18S,19S,22S,23S,25R)-1,10,11,12,14,23-hexahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] 3,4-dimethoxybenzoate | HMS1791L17 | Cevane-3,4,12,14,16,17,

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Hoja de especificaciones

Descripción general Especificaciones Nombres e identificadores Documentación Datos avanzados Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Preguntas frecuentes y artículos Calculadoras de soluciones Reseñas

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Por qué esta calidad

Moligand™, ≥97% Moligand™ para flujos de trabajo cromatográficos y analíticos sensibles que requieren una interferencia mínima de la línea base.

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Almacenamiento y envío

Store at -20°C,Desiccated Envío Ice chest + Ice pads. Consulte el COA específico del lote para conocer las especificaciones exactas.

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Documentos de calidad

SDS, COA, ficha técnica y hoja de especificaciones disponibles para descargar. COA específico del lote accesible mediante búsqueda por número de lote.

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Prueba documental

Citado en 0 publicaciones revisadas por pares sobre cromatografía, síntesis orgánica y reacciones de acoplamiento cruzado.

Descripción general

A Na+ channel opener. Increases intracellular Ca2+ levels without affecting Na+ - Ca2+ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. Induces cell death in bovine chromaffin cells.

Especificaciones

Sinónimos

Especificaciones y pureza

Moligand™, ≥97%

Mecanismos bioquímicos y fisiológicos

Alkaloid toxin found in Liliaceae plants. Causes persistent opening of the voltage-gated Na + channel and reduces its single-channel conductance. Channel opener.

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

ACTIVATOR

Mecanismo de acción

Activator of Na v1.1;Activator of Na v1.2;Activator of Na v1.3;Activator of Na v1.4;Activator of Na v1.5;Activator of Na v1.6;Activator of Na v1.7;Activator of Na v1.8

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥97%

Nombres e identificadores

Pubchem Sid

504751052

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504751052

Sonrisas canónicas

CC1CCC2C(C3(C(CC4(C5CCC6C7(C5(CC4(C3CN2C1)O)OC6(C(CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O

IUPAC Name

[(1R,2S,6S,9S,10R,11S,12S,14R,15S,18S,19S,22S,23S,25R)-1,10,11,12,14,23-hexahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] 3,4-dimethoxybenzoate

InChIKey

FVECELJHCSPHKY-YFUMOZOISA-N

INCHI

1S/C36H51NO11/c1-19-6-11-26-31(3,40)35(43)25(17-37(26)16-19)33(42)18-34-24(32(33,41)15-27(35)38)10-9-23-30(34,2)13-12-28(36(23,44)48-34)47-29(39)20-7-8-21(45-4)22(14-20)46-5/h7-8,14,19,23-28,38,40-44H,6,9-13,15-18H2,1-5H3/t19-,23-,24-,25-,26-,27-,28-,30-,31+,32+,33+,34+,35-,36-/m0/s1

Isómeros SMILES

C[C@H]1CC[C@H]2[C@@]([C@]3([C@H](C[C@]4([C@@H]5CC[C@H]6[C@]7([C@]5(C[C@]4([C@@H]3CN2C1)O)O[C@@]6([C@H](CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O

PubChem CID

6280

Peso molecular

673.8

Documentación

📋 Hoja de datos de seguridad (SDS)

Documento completo sobre peligros, manipulación, almacenamiento y cumplimiento normativo.

<<<<<<< HEAD Descargar SDS → ======= Descargar SDS → >>>>>>> release248-p3

✅ Certificado de análisis (COA)

Datos de calidad específicos del lote. Introduzca su número de lote para obtener el COA exacto.

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📊 Ficha técnica

Resumen de referencia rápida de las especificaciones y aplicaciones del producto.

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Atributos de calidad completos y criterios de aceptación para esta calidad.

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Datos avanzados

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Clase Steroids and steroid derivatives
    - Subclass Steroidal alkaloids

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Clase	Steroids and steroid derivatives
Subclass	Steroidal alkaloids
Intermediate Tree Nodes	Not available
Direct Parent	Cerveratrum-type alkaloids
Alternative Parents	Azasteroids and derivatives M-methoxybenzoic acids and derivatives P-methoxybenzoic acids and derivatives Benzoic acid esters Dimethoxybenzenes Quinolizidines Alkaloids and derivatives Phenoxy compounds Anisoles Benzoyl derivatives Oxepanes Alkyl aryl ethers Piperidines Tertiary alcohols Tetrahydrofurans Secondary alcohols Amino acids and derivatives Trialkylamines Hemiacetals Cyclic alcohols and derivatives Carboxylic acid esters 1,2-aminoalcohols Oxacyclic compounds Polyols Monocarboxylic acids and derivatives Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Cerveratrum-type alkaloid - Azasteroid - M-methoxybenzoic acid or derivatives - P-methoxybenzoic acid or derivatives - Benzoate ester - Quinolizidine - Dimethoxybenzene - O-dimethoxybenzene - Benzoic acid or derivatives - Alkaloid or derivatives - Anisole - Phenoxy compound - Benzoyl - Phenol ether - Methoxybenzene - Oxepane - Alkyl aryl ether - Benzenoid - Piperidine - Monocyclic benzene moiety - Tetrahydrofuran - Tertiary alcohol - Cyclic alcohol - Tertiary amine - Secondary alcohol - Amino acid or derivatives - Tertiary aliphatic amine - 1,2-aminoalcohol - Carboxylic acid ester - Hemiacetal - Oxacycle - Azacycle - Organoheterocyclic compound - Polyol - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Ether - Alcohol - Organooxygen compound - Organic nitrogen compound - Organic oxygen compound - Organonitrogen compound - Amine - Hydrocarbon derivative - Organopnictogen compound - Organic oxide - Aromatic heteropolycyclic compound
Descripción	This compound belongs to the class of organic compounds known as cerveratrum-type alkaloids. These are steroidal alkaloids containing the cevane (23-methyl-4- azahexacyclo[12.11.0.0^{2,11}.0^{4,9}.0^{15,24}.0^{18,23}]pentacosane) moiety, which is a six ring system. Cerveratrum alkaloids have 7-9 oxygen atoms and occur as free alkamines or esters of simple aliphatic or aromatic acids.
External Descriptors	steroid
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estructura 3D

Objetivos asociados (humanos)

SCN2A Tclin Sodium channel protein type 2 subunit alpha (1 Activities)

Discover Target: SCN2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SCN5A Tclin Sodium channel protein type 5 subunit alpha (1 Activities)

Discover Target: SCN5A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SCN10A Tclin Sodium channel protein type 10 subunit alpha (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SCN3A Tclin Sodium channel protein type 3 subunit alpha (0 Activities)

Discover Target: SCN3A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SCN9A Tclin Sodium channel protein type 9 subunit alpha (0 Activities)

Discover Target: SCN9A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SCN4A Tclin Sodium channel protein type 4 subunit alpha (0 Activities)

Discover Target: SCN4A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SCN1A Tclin Sodium channel protein type 1 subunit alpha (0 Activities)

Discover Target: SCN1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SCN8A Tclin Sodium channel protein type 8 subunit alpha (0 Activities)

Discover Target: SCN8A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ATIC Tchem AICAR transformylase (241 Activities)

Discover Target: ATIC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	Fecha	Articulo
L2202473	Certificate of Analysis	Sep 07, 2026	V275475
L2202488	Certificate of Analysis	Sep 07, 2026	V275475
F2601408	Certificate of Analysis	May 21, 2026	V275475
F2601409	Certificate of Analysis	May 21, 2026	V275475
F2601410	Certificate of Analysis	May 21, 2026	V275475
F2601429	Certificate of Analysis	May 21, 2026	V275475

Solubilidad	Soluble in ethanol to 100 mM
Peso molecular	673.800 g/mol
XLogP3	1.000
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	5
Exact Mass	673.346 Da
Monoisotopic Mass	673.346 Da
Topological Polar Surface Area	179.000 Å²
Heavy Atom Count	48
Formal Charge	0
Complexity	1340.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	14
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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