Vitamin D2 - Moligand™,10mM in DMSO , CAS No.50-14-6

CAS: 50-14-6 Cat. No.: V408904 Peso molecular: 396.65 Beilstein Registry Number: 1916682 Número EC: 200-014-9 PubChem CID: 5280793

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

Ergocalciferol | Cyclohexanol, 4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-, (1S,3Z)-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Vitamin D2 Vitamin D2 (Ergocalciferol) is a selective inhibitor of mammalian DNA polymerase A (pol A) with IC50 of 123 μM.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

Ergocalciferol | Cyclohexanol, 4-methylene-3-[(2E)-2-[(1R, 3aS, 7aR)-octahydro-7a-methyl-1-[(1R, 2E, 4R)-1, 4, 5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-, (1S, 3Z)-

Especificaciones y pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Vitamin D2 (Ergocalciferol) is a selective inhibitor of mammalian DNA polymerase A (pol A) with IC50 of 123 μM.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Propiedades del producto

• ALogP: 7.4

Nombres e identificadores

• Isómeros SMILES: C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C
• WGK Alemania: 2
• RTECS: KE1050000
• PubChem CID: 5280793
• Número ONU: 2811
• Grupo de embalaje: I
• Peso molecular: 396.65
• Beilstein: 1916682

Propiedades químicas y físicas

• Rotación específica [α]: +100 to +109 deg(C=1.5, EtOH)
• Punto de fusión (°C): 111-116°C

Referencias

1. Ling-Li Zheng, Guan Wen, Yun-Xin Yao, Xiao-Huan Li, Feng Gao.  (2020)  Design, Synthesis, and Anticancer Activity of Natural Product Hybrids With Paclitaxel Side Chain Inducing Apoptosis in Human Colon Cancer Cells.  Natural Product Communications,      [PMID:] [10.1177/1934578X20917298]

2. Cai Tongji, Chen Meilun, Yang Jie, Tang Chunhua, Lu Xiaoling, Wei Zheng, Jiang Hanbing, Hou Yucui, Zhao Jia, Yu Peng.  (2024)  An AuNPs-based electrochemical aptasensor for the detection of 25-hydroxy vitamin D3.  ANALYTICAL SCIENCES,      [PMID:38190076] [10.1007/s44211-023-00489-0]

3. Lixin Kang, Haoran Li, Kexin Lin, Shen Hu, Song Liu, Yuben Qiao, Ying Wang, Aitao Li.  (2025)  Regioselectivity Switching in CYP107Pdh-Catalyzed VD3 Hydroxylation: A Structure-Guided Approach To Improve Calcidiol Production.  ACS Catalysis,      [PMID:] [10.1021/acscatal.5c00444]

4. Huang Kun, Wang Dan-Dan, Hu Wen-Bao, Zeng Wei-Qian, Xu Xia, Li Qiu-Xiang, Bi Fang-Fang, Yang Huan, Qiu Jian.  (2022)  Calcitriol increases MBNL1 expression and alleviates myotonic dystrophy phenotypes in HSALR mouse models.  Journal of Translational Medicine,  20  (1): (1-10).  [PMID:36510245] [10.1186/s12967-022-03806-9]

5. Fengyan Tang, Bo Zhao, Li Zhang, Faisal Raza, Hajra Zafar, Shao Zhong, Lin Li, Wenhua Zhu, Lingna Fang, Bing Lu, Liwen Shen, Ping Guo, Nengxing Yu, Quanmin Li.  (2024)  Co-treatment of Astragaloside IV with Vitamin D in Diabetic Peripheral Neuropathic Rats: Protective Effects and Potential Mechanisms.  Current Molecular Pharmacology,  17  (1): (e18761429267000).  [PMID:38254301] [10.2174/0118761429267000231004111024]