Voclosporin, Inhibitor of peptidylprolyl isomerase A, CAS No.515814-01-4, Inhibitor of peptidylprolyl isomerase A

CAS: 515814-01-4 Cat. No.: V1491437 Peso molecular: 1214.62 Número EC: 881-570-5

GRADE & PURITY Moligand™, ≥98%

Descripción general

Voclosporin (ISAtx-247) is a calcineurin (CN; PP2B) inhibitor.

Specifications

Product Name

Voclosporin, Inhibitor of peptidylprolyl isomerase A, CAS No.515814-01-4

Sinónimos

ISAtx-247 | (3S, 6S, 9S, 12R, 15S, 18S, 21S, 24S, 30S, 33S)-30-Ethyl-33-((1R, 2R, E)-1-hydroxy-2-methylhepta-4, 6-dien-1-yl)-6, 9, 18, 24-tetraisobutyl-3, 21-diisopropyl-1, 4, 7, 10, 12, 15, 19, 25, 28-nonamethyl-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31-undecaazacyclotritriacontan-2, 5, 8, 11

Grado

Moligand™

Especificaciones y pureza

Moligand™, ≥98%

Tipo de acción

INHIBITOR

Mecanismo de acción

Inhibitor of peptidylprolyl isomerase A

CAS

515814-01-4

Tipo de molécula

Small molecule

Almacenamiento y envío

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Peptidomimetics
      • Subclass Peptoid-peptide hybrids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Peptidomimetics
• Subclass: Peptoid-peptide hybrids
• Intermediate Tree Nodes: Not available
• Direct Parent: Cyclosporins
• Alternative Parents: Oligopeptides Macrolactams Alpha amino acids and derivatives Tertiary carboxylic acid amides Secondary carboxylic acid amides Secondary alcohols Lactams Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Cyclosporin-backbone - Alpha-oligopeptide - Macrolactam - Alpha-amino acid or derivatives - Tertiary carboxylic acid amide - Carboxamide group - Lactam - Secondary alcohol - Secondary carboxylic acid amide - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Alcohol - Organic oxygen compound - Carbonyl group - Organooxygen compound - Organic nitrogen compound - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as cyclosporins. These are cyclic depsipeptides containing the cyclosporin backbone.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Información genética

• Alternate Names: ISAtx-247 | (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhepta-4,6-dien-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11
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