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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Y-29794 tosylate is a selective, orally active inhibitor for non-peptide prolyl endopeptidase ( PREP ), with an IC 50 of 3 nM and a K i of 0.95 nM. Y-29794 tosylate enhances the effect of thyrotropin-releasing hormone ( TRH ) on the release of ACh in the rat hippocampus, exhibits potential neuroprotective efficacy. Y-29794 tosylate exhibits anticancer activity through inhibition of the IRS1-AKT-mTORC1 pathway. Y-29794 tosylate penetrates the brain-blood barrier (BBB).
| Sonrisas canónicas | CC1=CC=C(C=C1)S(=O)(=O)O.CC(C)C1=NC(=C(C=C1)C(=O)C2=CC=CS2)SCCCCCCCCN(C)C |
|---|---|
| IUPAC Name | [2-[8-(dimethylamino)octylsulfanyl]-6-propan-2-ylpyridin-3-yl]-thiophen-2-ylmethanone;4-methylbenzenesulfonic acid |
| InChIKey | CSLUSHFIPGHVIY-UHFFFAOYSA-N |
| INCHI | 1S/C23H34N2OS2.C7H8O3S/c1-18(2)20-14-13-19(22(26)21-12-11-17-27-21)23(24-20)28-16-10-8-6-5-7-9-15-25(3)4;1-6-2-4-7(5-3-6)11(8,9)10/h11-14,17-18H,5-10,15-16H2,1-4H3;2-5H,1H3,(H,8,9,10) |
| Isómeros SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.CC(C)C1=NC(=C(C=C1)C(=O)C2=CC=CS2)SCCCCCCCCN(C)C |
| PubChem CID | 9851449 |
| Términos de entrada MeSH | 2-(8-dimethylaminooctylthio)-6-isopropyl-3-pyridyl-2-thienyl ketone citrate;Y 29794;Y-29794;Y29794 |
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