≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
YF-2 YF-2 is a highly selective, blood-brain-barrier permeable activator of histone acetyltransferase (HAT) . In In vitro assays, YF-2 has activity versus CBP, PCAF, and GCN5 with EC50 of 2.75 μΜ, 29.04 μΜ and 49.3 μΜ, respectively. YF-2 also increases p300 activity.
Targets
HAT ; p300 ; CBP (Cell-based assay); PCAF (Cell-based assay); GCN5 (Cell-based assay) ; 2.75 μM(EC50); 29.04 μM(EC50); 49.3 μM(EC50)
| ALogP | 4.676 |
|---|---|
| Recuento HBD | 1 |
| Enlace rotable | 9 |
| Pubchem Sid | 488201556 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488201556 |
| Sonrisas canónicas | CCOC1=C(C(=CC=C1)OCCN(C)C)C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F |
| IUPAC Name | N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)ethoxy]-6-ethoxybenzamide |
| InChIKey | TZHLDFAKTWDTOW-UHFFFAOYSA-N |
| INCHI | 1S/C20H22ClF3N2O3/c1-4-28-16-6-5-7-17(29-11-10-26(2)3)18(16)19(27)25-13-8-9-15(21)14(12-13)20(22,23)24/h5-9,12H,4,10-11H2,1-3H3,(H,25,27) |
| Isómeros SMILES | CCOC1=C(C(=CC=C1)OCCN(C)C)C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F |
| PubChem CID | 53230697 |
| Peso molecular | 430.85 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
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View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Anilides |
| Intermediate Tree Nodes | Aromatic anilides |
| Direct Parent | Benzanilides |
| Alternative Parents | Trifluoromethylbenzenes Benzamides Benzoyl derivatives Phenol ethers Phenoxy compounds Chlorobenzenes Alkyl aryl ethers Aryl chlorides Trialkylamines Amino acids and derivatives Secondary carboxylic acid amides Organopnictogen compounds Organofluorides Organochlorides Organic oxides Hydrocarbon derivatives Alkyl fluorides |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Benzanilide - Trifluoromethylbenzene - Benzamide - Benzoic acid or derivatives - Phenoxy compound - Benzoyl - Phenol ether - Alkyl aryl ether - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Amino acid or derivatives - Tertiary aliphatic amine - Carboxamide group - Tertiary amine - Secondary carboxylic acid amide - Ether - Carboxylic acid derivative - Organic nitrogen compound - Amine - Alkyl halide - Alkyl fluoride - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organohalogen compound - Organochloride - Organofluoride - Organonitrogen compound - Organooxygen compound - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as benzanilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with a benzene ring. They have the general structure RNC(=O)R', where R,R'= benzene. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 E2627142 | Certificate of Analysis | Jun 05, 2026 | Y412127 |
| E2309191 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| E2309192 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| E2309193 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| E2309194 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| E2309195 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| E2309203 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| E2309233 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| E2309235 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| E2309242 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| E2309733 | Certificate of Analysis | Feb 05, 2026 | Y412127 |
| Solubilidad | Solubility (25°C) In vitro DMSO: 86 mg/mL (199.6 mM); Water: 86 mg/mL (199.6 mM); Ethanol: 86 mg/mL (199.6 mM); |
|---|---|
| DMSO (mg/ml) Solubilidad máxima | 86 |
| DMSO (mM) Solubilidad máxima | 199.605431124521 |
| Agua (mg/ml) Solubilidad máxima | 86 |
| Agua (mM) Solubilidad máxima | 199.605431124521 |
| Peso molecular | 430.800 g/mol |
| XLogP3 | 4.600 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 8 |
| Exact Mass | 430.127 Da |
| Monoisotopic Mass | 430.127 Da |
| Topological Polar Surface Area | 50.800 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 522.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
