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≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
YM-53601 inhibits squalene synthetase activity in rat hepatic microsomes and human HepG2 cells. YM-53601 can also inhibit cholesterol biosynthesis (ED|50|= 32 mg/kg), causing a reduction in both cholesterol and triglyceride levels in plasma. The lipid-lowering properties of compounds such as YM-53601 make them interesting research opportunities for alternatives to combination HMG-CoA reductase inhibitor/fibrate therapy.
| Sonrisas canónicas | C1CN2CCC1C(=C(COC3=CC4=C(C=C3)C5=CC=CC=C5N4)F)C2.Cl |
|---|---|
| IUPAC Name | 2-[2-(1-azabicyclo[2.2.2]octan-3-ylidene)-2-fluoroethoxy]-9H-carbazole;hydrochloride |
| InChIKey | JWXYVHMBPISIJQ-UHFFFAOYSA-N |
| INCHI | 1S/C21H21FN2O.ClH/c22-19(18-12-24-9-7-14(18)8-10-24)13-25-15-5-6-17-16-3-1-2-4-20(16)23-21(17)11-15;/h1-6,11,14,23H,7-10,12-13H2;1H |
| Isómeros SMILES | C1CN2CCC1C(=C(COC3=CC4=C(C=C3)C5=CC=CC=C5N4)F)C2.Cl |
| WGK Alemania | 3 |
| PubChem CID | 9907532 |
| Peso molecular | 372.86 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Oct 30, 2024 | Y332775 | |
| Certificate of Analysis | Oct 30, 2024 | Y332775 | |
| Certificate of Analysis | Oct 30, 2024 | Y332775 | |
| Certificate of Analysis | Oct 30, 2024 | Y332775 | |
| Certificate of Analysis | Oct 30, 2024 | Y332775 | |
| Certificate of Analysis | Oct 30, 2024 | Y332775 | |
| Certificate of Analysis | Oct 30, 2024 | Y332775 | |
| Certificate of Analysis | Oct 30, 2024 | Y332775 | |
| Certificate of Analysis | Oct 30, 2024 | Y332775 | |
| Certificate of Analysis | Oct 30, 2024 | Y332775 |
| Solubilidad | Soluble in ethanol (~2 mg/ml), DMSO (22 mg/ml), DMF (~20 mg/ml), and 1:3 solution of DMSO:PBS(pH7.2) (~0.25 mg/ml). |
|---|---|
| Sensibilidad | Moisture sensitive |
| Índice de refracción | n20D~1.69 (Predicted) |
| Punto de fusión (°C) | 236.5-237.2° C |