Zaltidine - ≥98% , CAS No.85604-00-8

CAS: 85604-00-8 Cat. No.: Z127855 Peso molecular: 222.27 PubChem CID: 56051

GRADE & PURITY ≥98%

Synonyms

(4-(2-METHYLIMIDAZOL-5-YL)-2-THIAZOLYL)QUANIDINE | 85604-00-8 (free base) | A914628 | F84942 | GUANIDINE, (4-(2-METHYL-1H-IMIDAZOL-5-YL)-2-THIAZOLYL)- | GIMNAEMRNXUAQP-UHFFFAOYSA-N | Zaltidina [Spanish] | 1-(4-(2-methyl-1H-imidazol-4-yl)thiazol-2-yl)guani

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

(4-(2-METHYLIMIDAZOL-5-YL)-2-THIAZOLYL)QUANIDINE | 85604-00-8 (free base) | A914628 | F84942 | GUANIDINE, (4-(2-METHYL-1H-IMIDAZOL-5-YL)-2-THIAZOLYL)- | GIMNAEMRNXUAQP-UHFFFAOYSA-N | Zaltidina [Spanish] | 1-(4-(2-methyl-1H-imidazol-4-yl)thiazol-2-yl)guani

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Description:
IC50 Value: N/A
Zaltidine is a H2-receptor antagonist, which has the antisecretory action.
in vitro: N/A
in vivo: In eight healthy male volunteers single oral doses of 5 mg, 25 mg and 100 mg produced dose-

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: CC1=NC=C(N1)C2=CSC(=N2)N=C(N)N
• IUPAC Name: 2-[4-(2-methyl-1H-imidazol-5-yl)-1,3-thiazol-2-yl]guanidine
• InChIKey: GIMNAEMRNXUAQP-UHFFFAOYSA-N
• INCHI: 1S/C8H10N6S/c1-4-11-2-5(12-4)6-3-15-8(13-6)14-7(9)10/h2-3H,1H3,(H,11,12)(H4,9,10,13,14)
• Isómeros SMILES: CC1=NC=C(N1)C2=CSC(=N2)N=C(N)N
• PubChem CID: 56051
• Peso molecular: 222.27

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Azoles
      • Subclass Thiazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Azoles
• Subclass: Thiazoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 2,4-disubstituted thiazoles
• Alternative Parents: Imidazoles Heteroaromatic compounds Guanidines Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 2,4-disubstituted 1,3-thiazole - Heteroaromatic compound - Imidazole - Guanidine - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as 2,4-disubstituted thiazoles. These are compounds containing a thiazole ring substituted at the positions 2 and 3.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

HRH2 Tclin Histamine H2 receptor (5428 Activities)

Discover Target: HRH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Canis familiaris (36305 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: DMSO
• Peso molecular: 222.270 g/mol
• XLogP3: 0.000
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 222.069 Da
• Monoisotopic Mass: 222.069 Da
• Topological Polar Surface Area: 134.000 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 254.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1