Zandatrigine - ≥99% , Sodium channel protein type VIII alpha subunit inhibitor, CAS No.2154406-04-7, Sodium channel protein type VIII alpha subunit inhibitor

CAS: 2154406-04-7 Cat. No.: Z651073 Peso molecular: 460.59 PubChem CID: 132141687

GRADE & PURITY ≥99%

Synonyms

Zandatrigine | BDBM470680 | Benzenesulfonamide, 2-fluoro-5-methyl-4-(methyl((3S)-1-(phenylmethyl)-3-pyrrolidinyl)amino)-N-4-thiazolyl- | SV2WPA4R4J | AKOS040757364 | SCHEMBL19613237 | NBI-921352 | NBI921352 | zandatrigine [INN] | 4-[[(3S)-1-benzylpyrrolid

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Zandatrigine (NBI-921352) is a sodium channel protein type 8 subunit alpha (Scn8α) blocker

Form:Solid

IC50& Target:Scn8α

Specifications

Sinónimos

Zandatrigine | BDBM470680 | Benzenesulfonamide, 2-fluoro-5-methyl-4-(methyl((3S)-1-(phenylmethyl)-3-pyrrolidinyl)amino)-N-4-thiazolyl- | SV2WPA4R4J | AKOS040757364 | SCHEMBL19613237 | NBI-921352 | NBI921352 | zandatrigine [INN] | 4-[[(3S)-1-benzylpyrrolid

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

Zandatrigine (NBI-921352) is a sodium channel protein type 8 subunit alpha (Scn8α) blocker.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Mecanismo de acción

Sodium channel protein type VIII alpha subunit inhibitor

Pureza

≥99%

Propiedades del producto

• ALogP: 4.1

Nombres e identificadores

• Sonrisas canónicas: CC1=CC(=C(C=C1N(C)[C@H]2CCN(C2)CC3=CC=CC=C3)F)S(=O)(=O)NC4=CSC=N4
• IUPAC Name: 4-[[(3S)-1-benzylpyrrolidin-3-yl]-methylamino]-2-fluoro-5-methyl-N-(1,3-thiazol-4-yl)benzenesulfonamide
• InChIKey: UCSHINHOAVARGQ-SFHVURJKSA-N
• INCHI: 1S/C22H25FN4O2S2/c1-16-10-21(31(28,29)25-22-14-30-15-24-22)19(23)11-20(16)26(2)18-8-9-27(13-18)12-17-6-4-3-5-7-17/h3-7,10-11,14-15,18,25H,8-9,12-13H2,1-2H3/t18-/m0/s1
• Isómeros SMILES: CC1=CC(=C(C=C1N(C)[C@H]2CCN(C2)CC3=CC=CC=C3)F)S(=O)(=O)NC4=CSC=N4
• PubChem CID: 132141687
• Peso molecular: 460.59

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Benzene and substituted derivatives
      • Subclass Benzenesulfonamides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Benzene and substituted derivatives
• Subclass: Benzenesulfonamides
• Intermediate Tree Nodes: Not available
• Direct Parent: Aminobenzenesulfonamides
• Alternative Parents: Phenylmethylamines Dialkylarylamines Benzylamines Aniline and substituted anilines Fluorobenzenes Aralkylamines N-alkylpyrrolidines Imidolactams Thiazoles Sulfonyls Organosulfonic acids and derivatives Heteroaromatic compounds Trialkylamines Azacyclic compounds Organopnictogen compounds Organofluorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Aminobenzenesulfonamide - Aniline or substituted anilines - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Phenylmethylamine - Benzylamine - Aralkylamine - Halobenzene - Fluorobenzene - Imidolactam - N-alkylpyrrolidine - Heteroaromatic compound - Thiazole - Sulfonyl - Organosulfonic acid or derivatives - Pyrrolidine - Azole - Tertiary aliphatic amine - Tertiary amine - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Amine - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: DMSO : 125 mg/mL (271.39 mM; Need ultrasonic)