ZK 200775 - Moligand™, ≥99%(HPLC) , CAS No.161605-73-8

CAS: 161605-73-8 Cat. No.: Z287426 Peso molecular: 409.25
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
Synonyms
GTPL7636 | NCGC00159553-01 | Tox21_111745_1 | ZK1 | NCGC00159553-02 | UNII-E3AP71EM0O | ZK 200775 | HMS3413G20 | HMS3677G20 | ZK200775 161605-73-8 | DB12393 | DTXSID7046093 | [7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]methylphospho
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
Z287426-1mg
3
42,90US$
5mg
Z287426-5mg
3
174,90US$
25mg
Z287426-25mg
2
591,90US$
100mg
Z287426-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
1.667,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥99%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Product description

Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively.


Specifications

Sinónimos
GTPL7636 | NCGC00159553-01 | Tox21_111745_1 | ZK1 | NCGC00159553-02 | UNII-E3AP71EM0O | ZK 200775 | HMS3413G20 | HMS3677G20 | ZK200775 161605-73-8 | DB12393 | DTXSID7046093 | [7-morpholin-4-yl-2, 3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]methylphospho
Especificaciones y pureza
Moligand™, ≥99%(HPLC)
Mecanismos bioquímicos y fisiológicos
Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (Ki= 120 nM) and [3H]-CNQX (Ki= 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC50values range from 2.5 to
Condiciones de almacenamiento de almacenamiento
Store at -20°C, Desiccated
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Pureza
≥99%(HPLC)
Nombres e identificadores
Sonrisas canónicasC1COCCN1C2=CC3=C(C=C2C(F)(F)F)NC(=O)C(=O)N3CP(=O)(O)O
IUPAC Name[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]methylphosphonic acid
InChIKeyWZMQMKNCWDCCMT-UHFFFAOYSA-N
INCHI1S/C14H15F3N3O6P/c15-14(16,17)8-5-9-11(6-10(8)19-1-3-26-4-2-19)20(7-27(23,24)25)13(22)12(21)18-9/h5-6H,1-4,7H2,(H,18,21)(H2,23,24,25)
Isómeros SMILES C1COCCN1C2=CC3=C(C=C2C(F)(F)F)NC(=O)C(=O)N3CP(=O)(O)O
CAS alternativo 1255517-78-2
Peso molecular 409.25

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseDiazanaphthalenes
SubclassBenzodiazines
Intermediate Tree Nodes Not available
Direct ParentQuinoxalines
Alternative Parents Dialkylarylamines  Benzenoids  Pyrazines  Morpholines  Organic phosphonic acids  Heteroaromatic compounds  Lactams  Azacyclic compounds  Dialkyl ethers  Oxacyclic compounds  Organofluorides  Organic oxides  Alkyl fluorides  Hydrocarbon derivatives  Organophosphorus compounds  Organopnictogen compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Quinoxaline - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Morpholine - Oxazinane - Pyrazine - Benzenoid - Heteroaromatic compound - Organophosphonic acid - Organophosphonic acid derivative - Tertiary amine - Lactam - Azacycle - Oxacycle - Dialkyl ether - Ether - Organic oxide - Organooxygen compound - Organonitrogen compound - Organofluoride - Organophosphorus compound - Alkyl halide - Organohalogen compound - Alkyl fluoride - Amine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as quinoxalines. These are compounds containing a quinoxaline moiety, a bicyclic heterocycle made up of a benzene ring fused to a pyrazine ring.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Xenopus sp. (29 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor (6467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gria2 Glutamate receptor ionotropic, AMPA (2103 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeFechaArticulo
H2529616Certificate of AnalysisMay 19, 2025 Z287426
H2529617Certificate of AnalysisMay 19, 2025 Z287426
H2529618Certificate of AnalysisMay 19, 2025 Z287426
I2502764Certificate of AnalysisMay 19, 2025 Z287426
Propiedades químicas y físicas
SolubilidadSolvent:DMSO, Max Conc. mg/mL: 40.93, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 20.46, Max Conc. mM: 50
Peso molecular409.250 g/mol
XLogP3-0.500
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count3
Exact Mass409.065 Da
Monoisotopic Mass409.065 Da
Topological Polar Surface Area119.000 Ų
Heavy Atom Count27
Formal Charge0
Complexity650.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
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