GSK-3

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  1. GSK3β inhibitor II, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 478482-75-6 分子式: C14H10IN3OS 分子量: 395.22
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● 在庫あり — 米国 商品 #: G338641
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    技術識別子
    IUPAC名
    2-[(3-iodophenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole
    SMILES
    C1=CC(=CC(=C1)I)CSC2=NN=C(O2)C3=CC=NC=C3
    InChIKey
    ZRHRPGSSSVYBRG-UHFFFAOYSA-N
    InChI
    1S/C14H10IN3OS/c15-12-3-1-2-10(8-12)9-20-14-18-17-13(19-14)11-4-6-16-7-5-11/h1-8H,9H2
    同義語
    2-Thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]-oxadiazole | 2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl)-1,3,4-oxa...
  2. Lithium chloride monohydrate
    CAS: 85144-11-2 分子式: LiCI·H2O 分子量: 60.41
    ● 在庫あり — 米国 商品 #: L118859
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    技術識別子
    IUPAC名
    lithium;chloride;hydrate
    SMILES
    [Li+].O.[Cl-]
    InChIKey
    VXJIMUZIBHBWBV-UHFFFAOYSA-M
    InChI
    1S/ClH.Li.H2O/h1H;;1H2/q;+1;/p-1
    同義語
    AKOS015855094 | Lithium chloride hydrate, Puratronic? | lithium;chloride;hydrate | Lithium chloride, monohydrate (8CI...
  3. LY2090314, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 603288-22-8 EC番号: 110-218-9 分子式: C28H25FN6O3 分子量: 512.53
    固体 Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: L126079
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    技術識別子
    IUPAC名
    3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione
    SMILES
    C1CCN(CC1)C(=O)N2CCN3C=C(C4=CC(=CC(=C43)C2)F)C5=C(C(=O)NC5=O)C6=CN=C7N6C=CC=C7
    InChIKey
    HRJWTAWVFDCTGO-UHFFFAOYSA-N
    InChI
    1S/C28H25FN6O3/c29-18-12-17-15-34(28(38)32-7-3-1-4-8-32)11-10-33-16-20(19(13-18)25(17)33)23-24(27(37)31-26(23)36)21-14-30-22-6-2-5-9-35(21)22/h2,5-6,9show more
    同義語
    ?-(Trichloromethyl)-4-pyridineethanol | AS-56097 | Kinome_3681 | LY2090314 | LY-2090314 | LY 2090314 | NSC801005 | NS...
  4. TWS 119
    CAS: 1507095-58-0 PubChem CID: 90488884 分子式: C22H16F6N4O6 分子量: 546.38
    ● 在庫あり — 米国 商品 #: T288232
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    技術識別子
    IUPAC名
    3-[[6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol;2,2,2-trifluoroacetic acid
    SMILES
    C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O
    InChIKey
    XJEFPMFFWJTJSL-UHFFFAOYSA-N
    InChI
    1S/C18H14N4O2.2C2HF3O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14;2*3-2(4,5)1(6)7/h1-10,23H,19H2,(H,20,21,22);2*(H,6,show more
    同義語
    3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxyphenol ditrifluoroacetate
  5. 2B-(SP) (TFA)
    CAS: 186901-17-7 PubChem CID: 90488714 分子式: C71H123N26O29P 分子量: 1835.88 (free base basis)
    ● 在庫あり — 米国 商品 #: B287641
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    技術識別子
    IUPAC名
    (2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-show more
    SMILES
    CC(C)CC(C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NCC(=O)NC(COP(=O)(O)O)C(=O)N1CCCC1C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(show more
    InChIKey
    LBVCQYQHTKHZRY-APZQELAWSA-N
    InChI
    1S/C71H123N26O29P/c1-32(2)26-43(93-61(114)42(18-21-52(103)104)91-60(113)41(17-20-51(101)102)88-56(109)36(7)84-55(108)35(6)86-58(111)38(13-9-23-81-70(7show more
  6. R547, Cyclin-dependent kinase 4 inhibitor
    CAS: 741713-40-6 PubChem CID: 6918852 分子式: C18H21F2N5O4S 分子量: 441.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: R127351
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    技術識別子
    IUPAC名
    [4-amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl]-(2,3-difluoro-6-methoxyphenyl)methanone
    SMILES
    COC1=C(C(=C(C=C1)F)F)C(=O)C2=CN=C(N=C2N)NC3CCN(CC3)S(=O)(=O)C
    InChIKey
    JRNJNYBQQYBCLE-UHFFFAOYSA-N
    InChI
    1S/C18H21F2N5O4S/c1-29-13-4-3-12(19)15(20)14(13)16(26)11-9-22-18(24-17(11)21)23-10-5-7-25(8-6-10)30(2,27)28/h3-4,9-10H,5-8H2,1-2H3,(H3,21,22,23,24)
    同義語
    (4-amino-2-(1-(methylsulfonyl)piperidin-4-ylamino)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone | (4-Amino-2...
  7. AR-A014418, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 487021-52-3 EC番号: 637-170-6 分子式: C12H12N4O4S 分子量: 308.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: A126821
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    技術識別子
    IUPAC名
    1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea
    SMILES
    COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]
    InChIKey
    YAEMHJKFIIIULI-UHFFFAOYSA-N
    InChI
    1S/C12H12N4O4S/c1-20-9-4-2-8(3-5-9)6-13-11(17)15-12-14-7-10(21-12)16(18)19/h2-5,7H,6H2,1H3,(H2,13,14,15,17)
    同義語
    AM803946 | GSK 3b inhibitor VIII | Q27077900 | BDBM50229962 | 1276635-87-0 | AR-A014418, >=98% (HPLC), solid | GSK-3b...
  8. AZD2858, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 486424-20-8 EC番号: 690-692-6 分子式: C21H23N7O3S 分子量: 453.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● 在庫あり — 米国 商品 #: A126819
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    技術識別子
    IUPAC名
    3-amino-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-pyridin-3-ylpyrazine-2-carboxamide
    SMILES
    CN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N
    InChIKey
    FHCSBLWRGCOVPT-UHFFFAOYSA-N
    InChI
    1S/C21H23N7O3S/c1-27-9-11-28(12-10-27)32(30,31)17-6-4-15(5-7-17)18-14-24-20(22)19(26-18)21(29)25-16-3-2-8-23-13-16/h2-8,13-14H,9-12H2,1H3,(H2,22,24)(Hshow more
    同義語
    A871895 | 3-amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-2-pyrazinecarboxamide | AC-30277 | 3-a...
  9. AZD1080, Inhibitor of glycogen synthase kinase 3 alpha;Inhibitor of glycogen synthase kinase 3 beta
    CAS: 612487-72-6 分子式: C19H18N4O2 分子量: 334.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: A126905
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    技術識別子
    IUPAC名
    2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-1H-indole-5-carbonitrile
    SMILES
    C1COCCN1CC2=CN=C(C=C2)C3=C(NC4=C3C=C(C=C4)C#N)O
    InChIKey
    BLTVBQXJFVRPFK-UHFFFAOYSA-N
    InChI
    1S/C19H18N4O2/c20-10-13-1-3-16-15(9-13)18(19(24)22-16)17-4-2-14(11-21-17)12-23-5-7-25-8-6-23/h1-4,9,11,22,24H,5-8,12H2
    同義語
    1,3-DICHLOROPROPENE, (1E)- | 2-hydroxy-3-(5-(morpholinomethyl)pyridin-2-yl)-1H-indole-5-carbonitrile | AKOS026674123 ...
  10. Alsterpaullone, Inhibitor of cyclin dependent kinase 1;Inhibitor of glycogen synthase kinase 3 beta
    CAS: 237430-03-4 EC番号: 636-614-6 分子式: C16H11N3O3 分子量: 293.28
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: A274619
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    技術識別子
    IUPAC名
    9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one
    SMILES
    C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)[N+](=O)[O-]
    InChIKey
    OLUKILHGKRVDCT-UHFFFAOYSA-N
    InChI
    1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20)
    同義語
    BDBM7262 | EX-A4771 | HMS2043P15 | 9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one | J-015199 | BRD-K1751638...
  11. Indazole
    CAS: 271-44-3 EC番号: 205-978-4 分子式: C7H6N2 分子量: 118.14
    ● 在庫あり — 米国 商品 #: I157585
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    技術識別子
    IUPAC名
    1H-indazole
    SMILES
    C1=CC=C2C(=C1)C=NN2
    InChIKey
    BAXOFTOLAUCFNW-UHFFFAOYSA-N
    InChI
    1S/C7H6N2/c1-2-4-7-6(3-1)5-8-9-7/h1-5H,(H,8,9)
    同義語
    1,2-Benzopyrazole | F0918-7060 | F1918-0009 | Indazole, 6 | UNII-7C4VQE5C03 | 1H-indazol | EINECS 205-978-4 | FT-0627...
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よくある質問

Which compounds are listed for GSK-3?
Compounds associated with GSK-3 are grouped here under the Stem Cell/Wnt classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does GSK-3 sit within Stem Cell/Wnt?
GSK-3 is one target listing within the Stem Cell/Wnt classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from GSK-3?
For compounds listed under GSK-3, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for GSK-3?
Browse the parent Stem Cell/Wnt listing to reach targets neighbouring GSK-3, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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