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  1. RKRARKE
    CAS: 82801-73-8 PubChem CID: 134097 分子式: C38H74N18O10 分子量: 943.11
    ● 在庫あり — 米国 商品 #: R276094
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    技術識別子
    IUPAC名
    (2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-5-(diamishow more
    SMILES
    CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)N
    InChIKey
    OUKSKNTVYYVIMZ-DUJSLOSMSA-N
    InChI
    1S/C38H74N18O10/c1-21(29(59)52-26(13-8-20-50-38(46)47)33(63)54-24(11-3-5-17-40)34(64)56-27(35(65)66)14-15-28(57)58)51-31(61)25(12-7-19-49-37(44)45)55-show more
    同義語
    AKOS024456827 | Arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid | cGMP Dependent Kinase Inhibitor Peptide | ...
  2. PKG drug G1
    CAS: 374703-78-3 PubChem CID: 135402990 分子式: C13H11N3OS 分子量: 257.31
    10mM in DMSO
    ● 在庫あり — 米国 商品 #: P423688
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    技術識別子
    IUPAC名
    4-hydroxy-5-[(Z)-(2-methylindol-3-ylidene)methyl]-1,3-dihydroimidazole-2-thione
    SMILES
    CC1=NC2=CC=CC=C2C1=CC3=C(NC(=S)N3)O
    InChIKey
    BPJCCABLAZZIEJ-RMKNXTFCSA-N
    InChI
    1S/C13H11N3OS/c1-7-9(6-11-12(17)16-13(18)15-11)8-4-2-3-5-10(8)14-7/h2-6,17H,1H3,(H2,15,16,18)/b9-6+
    同義語
    4-​Imidazolidinone,5-​[(2-​methyl-​1H-​indol-​3-​yl)​methylene]​-​2-​thioxo-
  3. PKG drug G1
    CAS: 374703-78-3 PubChem CID: 135402990 分子式: C13H11N3OS 分子量: 257.31
    ● 在庫あり — 米国 商品 #: P412207
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    技術識別子
    IUPAC名
    4-hydroxy-5-[(Z)-(2-methylindol-3-ylidene)methyl]-1,3-dihydroimidazole-2-thione
    SMILES
    CC1=NC2=CC=CC=C2C1=CC3=C(NC(=S)N3)O
    InChIKey
    BPJCCABLAZZIEJ-RMKNXTFCSA-N
    InChI
    1S/C13H11N3OS/c1-7-9(6-11-12(17)16-13(18)15-11)8-4-2-3-5-10(8)14-7/h2-6,17H,1H3,(H2,15,16,18)/b9-6+
    同義語
    4-​Imidazolidinone,5-​[(2-​methyl-​1H-​indol-​3-​yl)​methylene]​-​2-​thioxo-
  4. Rp-8-pCPT-cGMPS sodium
    CAS: 208445-07-2 PubChem CID: 139600533 分子式: C16H14ClN5NaO6PS2 分子量: 525.86
    ◐ .受注生産 · 8~12週間 商品 #: R287755
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    技術識別子
    IUPAC名
    sodium;2-amino-8-(4-chlorophenyl)sulfanyl-9-(7-hydroxy-2-oxido-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-1H-purishow more
    SMILES
    C1C2C(C(C(O2)N3C4=C(C(=O)NC(=N4)N)N=C3SC5=CC=C(C=C5)Cl)O)OP(=S)(O1)[O-].[Na+]
    InChIKey
    JERAACMSJYSCBY-UHFFFAOYSA-M
    InChI
    1S/C16H15ClN5O6PS2.Na/c17-6-1-3-7(4-2-6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-8(27-14)5-26-29(25,30)28-11;/h1-4,8,10-11,14,23H,5H2,(H,25show more
    同義語
    8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3',5'-[hydrogen [P(R)]-phosphorothioate] sodium
  5. Rp-8-Br-cGMPS
    CAS: 150418-07-8 PubChem CID: 3035839 分子式: C10H11BrN5O6PS 分子量: 440.17
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .受注生産 · 8~12週間 商品 #: R275791
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    技術識別子
    IUPAC名
    (2R,5R)-2-(2-amino-8-bromopurin-9-yl)-5-(dihydroxyphosphinothioyloxymethyl)-2,5-dihydrofuran-3,4-diol
    SMILES
    C1=C2C(=NC(=N1)N)N(C(=N2)Br)C3C(=C(C(O3)COP(=S)(O)O)O)O
    InChIKey
    NKBRWLDMUXONRI-SPGJFGJESA-N
    InChI
    1S/C10H11BrN5O6PS/c11-9-14-3-1-13-10(12)15-7(3)16(9)8-6(18)5(17)4(22-8)2-21-23(19,20)24/h1,4,8,17-18H,2H2,(H2,12,13,15)(H2,19,20,24)/t4-,8-/m1/s1
    同義語
    DTXSID20933942 | Rp-8-BrcGMPS | (R)-8-Bromoguanosine cyclic 3',5'-(hydrogen phosphorothioate) | O-{[5-(8-Bromo-2-imin...
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よくある質問

How is the PKG listing put together?
It draws on reported PKG annotations within Stem Cell/Wnt and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a PKG modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the PKG entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for PKG compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For PKG work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the PKG compound I need is not listed?
Search by CAS number or SMILES first, since analogs of PKG compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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