(±)12-HEPE - ≥98%, A solution in ethanol , CAS No.81187-21-5

CAS: 81187-21-5 Cat. No.: H345165 분자식: C20H30O3 분자량: 318.45
주문 가능
GRADE & PURITY ≥98% A solution in ethanol
Synonyms
12-Hydroxyeicosapentaenoic acid | Metocryst | 12-Hydroxy-5,8,10,14,17-eicosapentaenoic acid | Q27140043 | SCHEMBL12970718 | 12-hydroxy-5Z,8Z,10E,14Z,17Z-icosapentaenoic acid | SR-01000946901-1 | (5Z,8Z,10E,14Z,17Z)-12-hydroxyeicosa-5,8,10,14,17-pentaenoic
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
독일 (EU)*
Price
Qty
25μg
H345165-25μg
1 재고 있음
—
US$473.90
50μg
H345165-50μg
주문제작 · 8~12주
US$778.90
100μg
H345165-100μg
주문제작 · 8~12주
US$1,542.90
250μg
H345165-250μg
주문제작 · 8~12주
US$3,501.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥98%, A solution in ethanol for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

(±)12-HEPE Produced by non-enzymatic oxidation of EPA, where it contains a racemic mixture. The biological activity is likely mediated by one of the individual isomers, most commonly the 12(S) isomer in mammalian systems. 12-HEPE inhibits platelet aggregation with the same potency as 12-HETE, exhibiting IC50 values of 24 and 25 μM, respectively. These compounds are also equipotent as inhibitors of U46619-induced contraction of rat aorta (IC50s = 8.6-8.8 μM).


application:

(+/-)12-HEPE is a compound which inhibits platelet aggregation.

Specifications

동의어
12-Hydroxyeicosapentaenoic acid | Metocryst | 12-Hydroxy-5,8,10,14,17-eicosapentaenoic acid | Q27140043 | SCHEMBL12970718 | 12-hydroxy-5Z,8Z,10E,14Z,17Z-icosapentaenoic acid | SR-01000946901-1 | (5Z,8Z,10E,14Z,17Z)-12-hydroxyeicosa-5,8,10,14,17-pentaenoic
사양 및 순도
≥98%, A solution in ethanol
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
순수함
≥98%
이름과 식별자
Pubchem Sid
정식 스마일
CCC=CCC=CCC(C=CC=CCC=CCCCC(=O)O)O
IUPAC Name
(5Z,8Z,10E,14Z,17Z)-12-hydroxyicosa-5,8,10,14,17-pentaenoic acid
InChIKey
MCRJLMXYVFDXLS-QGQBRVLBSA-N
INCHI
1S/C20H30O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h3-4,7-11,13-14,17,19,21H,2,5-6,12,15-16,18H2,1H3,(H,22,23)/b4-3-,9-7-,11-8-,13-10-,17-14+
이성체 SMILES
CC/C=C\C/C=C\CC(/C=C/C=C\C/C=C\CCCC(=O)O)O
분자량
318.45
Reaxy-Rn
29757819
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29757819&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
분류Fatty Acyls
SubclassEicosanoids
Intermediate Tree Nodes Not available
Direct ParentHydroxyeicosapentaenoic acids
Alternative Parents Long-chain fatty acids  Hydroxy fatty acids  Unsaturated fatty acids  Secondary alcohols  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Hydroxyeicosapentaenoic acid - Long-chain fatty acid - Hydroxy fatty acid - Fatty acid - Unsaturated fatty acid - Secondary alcohol - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxide - Organic oxygen compound - Alcohol - Hydrocarbon derivative - Carbonyl group - Organooxygen compound - Aliphatic acyclic compound
설명This compound belongs to the class of organic compounds known as hydroxyeicosapentaenoic acids. These are eicosanoic acids with an attached hydroxyl group and five CC double bonds.
External Descriptors Hydroxy/hydroperoxyeicosapentaenoic acids
3D 구조
상호 작용 화학 구조 모델





인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate Type날짜항목
K2212317Certificate of AnalysisJun 28, 2022 H345165
K2212419Certificate of AnalysisJun 28, 2022 H345165
H2202353Certificate of AnalysisJun 28, 2022 H345165
I2201530Certificate of AnalysisJun 28, 2022 H345165
화학 및 물리적 특성
끓는점(°C)78° C
분자량318.400 g/mol
XLogP34.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count13
Exact Mass318.219 Da
Monoisotopic Mass318.219 Da
Topological Polar Surface Area57.500 Ų
Heavy Atom Count23
Formal Charge0
Complexity428.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count5
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds5
Covalently-Bonded Unit Count1
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